关键词: Ureaplasma gastric fluid intra-amniotic infection prematurity preterm birth

Mesh : Humans Pregnancy Infant, Newborn Female Premature Birth / epidemiology etiology Retrospective Studies Amniotic Fluid Ureaplasma Parturition Chorioamnionitis / etiology

来  源:   DOI:10.1515/jpm-2023-0123

Abstract:
OBJECTIVE: To compare the frequency of Ureaplasma-positive gastric fluid (GF) cultures based on the cause and mode of delivery in preterm newborns.
METHODS: This retrospective cohort study included women with a singleton pregnancy who delivered prematurely (between 23+0 and 32+0 weeks of gestation, n=464) at a single university hospital in South Korea. The newborns\' GF was obtained on the day of birth via nasogastric intubation. The frequency of Ureaplasma spp. in GF cultures was measured and compared according to the cause and mode of delivery.
RESULTS: Ureaplasma spp. was detected in 20.3 % of the GF samples. The presence of Ureaplasma spp. was significantly higher in the spontaneous preterm birth group than in the indicated preterm birth group (30.2 vs. 3.0 %; p<0.001). Additionally, Ureaplasma spp. was more frequently found in the vaginal delivery group than in the cesarean delivery group, irrespective of the cause of preterm delivery [indicated preterm birth group (22.2 vs. 1.9 %, p=0.023); spontaneous preterm birth group (37.7 vs. 24.2 %, p=0.015)].
CONCLUSIONS: Ureaplasma spp. were found in 20.3 % of the GFs. However, only 1.9 % of newborns in the indicated preterm birth group with cesarean delivery had a Ureaplasma-positive GF culture.
摘要:
目的:根据早产新生儿的病因和分娩方式,比较脲原体阳性胃液(GF)培养的频率。
方法:这项回顾性队列研究包括单胎妊娠的妇女,她们早产(妊娠23+0至32+0周,n=464)在韩国的一所大学医院。新生儿GF是在出生当天通过鼻胃插管获得的。脲原体的频率。根据分娩的原因和方式对GF培养物进行了测量和比较。
结果:脲原体属。在20.3%的GF样品中检测到。脲原体属的存在。自发性早产组明显高于所示早产组(30.2vs.3.0%;p<0.001)。此外,脲原体属。阴道分娩组比剖宫产组更常见,无论早产的原因如何[所示早产组(22.2vs.1.9%,p=0.023);自发性早产组(37.7vs.24.2%,p=0.015)]。
结论:脲原体属。在20.3%的GFs中发现。然而,在指定的剖宫产早产组中,只有1.9%的新生儿有脲原体阳性GF培养.
公众号