关键词: PI3K/AKT/mTOR pathway colon carcinoma epithelial‑mesenchymal transition metastasis xenograft mouse model

来  源:   DOI:10.3892/ijmm.2023.5340   PDF(Pubmed)

Abstract:
Following the publication of this paper, it was drawn to the Editor\'s attention by a concerned reader that the immunofluorescence staining data shown in Fig. 3C, and the migration and invasion assay data shown in Figs. 4C and 4D were strikingly similar to data appearing in different form in other research articles written by different authors at different research institutes that had either already been published, or were submitted for publication at around the same time, one of which has been retracted. In addition, the western blotting data shown for the E‑cadherin and AKT protein bands in Fig. 5 were strikingly similar, albeit the bands had been flipped vertically. Owing to the fact that contentious data in the above article had already been submitted for publication elsewhere prior to its submission to International Journal of Molecular Medicine, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Molecular Medicine 44: 700‑708, 2020; DOI: 10.3892/ijmm.2020.4637].
摘要:
在本文发表之后,相关读者提请编辑注意图所示的免疫荧光染色数据。3C,以及迁移和侵袭试验数据如图所示。4C和4D与已经发表的不同作者在不同研究机构撰写的其他研究文章中以不同形式出现的数据惊人地相似。或者大约在同一时间提交出版,其中一个已经撤回。此外,图中显示的E‑cadherin和AKT蛋白条带的蛋白质印迹数据。5非常相似,尽管乐队已经垂直翻转。由于上述文章中的有争议的数据在提交给国际分子医学杂志之前已经提交到其他地方发表,编辑已经决定这篇论文应该从期刊上撤回。作者被要求解释这些担忧,但编辑部没有收到回复。编辑对读者造成的不便表示歉意。[国际分子医学杂志44:700-708,2020年;DOI:10.3892/ijmm.2020.4637]。
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