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Abstract：
UNASSIGNED: To analyse amniotic fluid volume (AFV), specifically oligohydramnios or polyhydramnios, and associated pregnancy and neonatal outcomes in twin gestations through systematic review and meta-analysis.
UNASSIGNED: We utilised systematic review methodology to identify items within published and grey literature resources. Prospective and retrospective studies with a control group were included. Inclusion criteria were as follows: studies in English, twin pregnancy in which AFVs and associated pregnancy and/or neonatal outcomes were evaluated. Exclusion criteria included the presence of an anomalous fetus, chromosome abnormality, monochorionic diamniotic twin pregnancy complicated by twin-twin transfusion syndrome or twin-reversed arterial perfusion, twin gestations undergoing therapeutic interventions (i.e. fetoscopic laser photocoagulation and serial amniocentesis) and monochorionic monoamniotic twin pregnancy.
UNASSIGNED: The literature search identified 1068 abstracts, only four met criteria for inclusion and analysis. The pooled data (two studies per outcome) revealed no significant difference in rate of pre-term delivery (OR: 2.94; CI: 0.20-43.81), pre-term delivery less than 32 weeks (OR: 1.97; CI: 0.43-9.12), umbilical cord pH < 7 (OR: 2.66; CI: 0.22-32.51), rate of stillbirth (OR: 4.13; CI: 0.40-42.70), neonatal death (OR: 1.48; CI: 0.05-43.94), rate of NICU admission (OR: 1.38; CI: 0.61-3.11) or rate of small-for-gestational-age (SGA) infants (OR: 1.39; CI: 0.33-5.94).
UNASSIGNED: Based on the pooled data (two studies per outcome), there was no difference in the fate of pre-term delivery, umbilical cord pH < 7, stillbirth, neonatal death or SGA infants. What is disturbing is the lack of studies (1946-2020) that analysed the association between AFV and pregnancy outcomes in twin pregnancies.
UNASSIGNED: We utilised systematic review methodology to identify items within published and grey literature resources. Prospective and retrospective studies with a control group were included. Inclusion criteria were as follows: studies in English, twin pregnancy in which AFVs and associated pregnancy and/or neonatal outcomes were evaluated. Exclusion criteria included the presence of an anomalous fetus, chromosome abnormality, monochorionic diamniotic twin pregnancy complicated by twin-twin transfusion syndrome or twin-reversed arterial perfusion, twin gestations undergoing therapeutic interventions (i.e. fetoscopic laser photocoagulation and serial amniocentesis) and monochorionic monoamniotic twin pregnancy.
UNASSIGNED: The literature search identified 1068 abstracts, only four met criteria for inclusion and analysis. The pooled data (two studies per outcome) revealed no significant difference in rate of pre-term delivery (OR: 2.94; CI: 0.20-43.81), pre-term delivery less than 32 weeks (OR: 1.97; CI: 0.43-9.12), umbilical cord pH < 7 (OR: 2.66; CI: 0.22-32.51), rate of stillbirth (OR: 4.13; CI: 0.40-42.70), neonatal death (OR: 1.48; CI: 0.05-43.94), rate of NICU admission (OR: 1.38; CI: 0.61-3.11) or rate of small-for-gestational-age (SGA) infants (OR: 1.39; CI: 0.33-5.94).
UNASSIGNED: Based on the pooled data (two studies per outcome), there was no difference in the fate of pre-term delivery, umbilical cord pH < 7, stillbirth, neonatal death or SGA infants. What is disturbing is the lack of studies (1946-2020) that analysed the association between AFV and pregnancy outcomes in twin pregnancies.
摘要：
■要分析羊水量（AFV），特别是羊水过少或羊水过多，通过系统评价和荟萃分析，双胎妊娠的相关妊娠和新生儿结局。
■我们利用系统审查方法来识别已发表和灰色文献资源中的项目。包括对照组的前瞻性和回顾性研究。纳入标准如下：英文研究，双胎妊娠，其中评估AFV和相关的妊娠和/或新生儿结局。排除标准包括异常胎儿的存在，染色体异常,单绒毛膜双胎双胎妊娠并发双胎输血综合征或双胎逆转动脉灌注，接受治疗性干预（即胎儿镜激光光凝和连续羊膜穿刺术）的双胎妊娠和单绒毛膜单羊膜双胎妊娠。
■文献检索确定了1068篇摘要，只有4人符合纳入和分析标准.汇总数据（每个结果两项研究）显示早产率没有显着差异（OR：2.94；CI：0.20-43.81），早产少于32周（OR：1.97；CI：0.43-9.12），脐带pH<7（OR：2.66；CI：0.22-32.51），死产率（OR：4.13；CI：0.40-42.70），新生儿死亡（OR：1.48；CI：0.05-43.94），NICU入院率(OR:1.38;CI:0.61-3.11)或小于胎龄(SGA)婴儿率(OR:1.39;CI:0.33-5.94)。
■基于汇总数据（每个结果两项研究），早产的命运没有区别，脐带pH<7，死胎，新生儿死亡或SGA婴儿。令人不安的是，缺乏分析双胎妊娠中AFV与妊娠结局之间关系的研究（1946-2020）。
■我们利用系统审查方法来识别已发表和灰色文献资源中的项目。包括对照组的前瞻性和回顾性研究。纳入标准如下：英文研究，双胎妊娠，其中评估AFV和相关的妊娠和/或新生儿结局。排除标准包括异常胎儿的存在，染色体异常,单绒毛膜双胎双胎妊娠并发双胎输血综合征或双胎逆转动脉灌注，接受治疗性干预（即胎儿镜激光光凝和连续羊膜穿刺术）的双胎妊娠和单绒毛膜单羊膜双胎妊娠。
■文献检索确定了1068篇摘要，只有4人符合纳入和分析标准.汇总数据（每个结果两项研究）显示早产率没有显着差异（OR：2.94；CI：0.20-43.81），早产少于32周（OR：1.97；CI：0.43-9.12），脐带pH<7（OR：2.66；CI：0.22-32.51），死产率（OR：4.13；CI：0.40-42.70），新生儿死亡（OR：1.48；CI：0.05-43.94），NICU入院率(OR:1.38;CI:0.61-3.11)或小于胎龄(SGA)婴儿率(OR:1.39;CI:0.33-5.94)。
■基于汇总数据（每个结果两项研究），早产的命运没有区别，脐带pH<7，死胎，新生儿死亡或SGA婴儿。令人不安的是，缺乏分析双胎妊娠中AFV与妊娠结局之间关系的研究（1946-2020）。
