PDF(Pubmed)
Abstract：
UNASSIGNED: In underdeveloped countries, there is a greater incidence of mortality and morbidity arising from trauma, with traumatic brain injury (TBI) accounting for 50% of all trauma-related deaths. The occurrence of elevated intracranial pressure (ICP), which is a common pathophysiological phenomenon in cases of TBI, acts as a contributing factor to unfavorable outcomes. The aim of this systematic review is to analyze the existing literature regarding the management of adult TBI with raised ICP in an intensive critical care unit, despite limited resources.
UNASSIGNED: This systematic review was performed in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis protocol. Search engines such as PubMed, the Cochrane database, and Google Scholar were utilized to locate high-level evidence that would facilitate the formation of sound conclusions.
UNASSIGNED: A total of 11 715 articles were identified and individually assessed to determine their eligibility for inclusion or exclusion based on predetermined criteria and outcome variables. The methodological quality of each study was evaluated using recommended criteria. Ultimately, the review consisted of 51 articles.
UNASSIGNED: Physical examination results and noninvasive assessments of the optic nerve sheath diameter (ONSD) via sonography are positively associated with elevated ICP, and are employed as diagnostic and monitoring tools for elevated ICP in resource-limited settings. Management of elevated ICP necessitates an algorithmic approach that utilizes prophylactic measures and acute intervention treatments to mitigate the risk of secondary brain injury.
UNASSIGNED: This systematic review was performed in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis protocol. Search engines such as PubMed, the Cochrane database, and Google Scholar were utilized to locate high-level evidence that would facilitate the formation of sound conclusions.
UNASSIGNED: A total of 11 715 articles were identified and individually assessed to determine their eligibility for inclusion or exclusion based on predetermined criteria and outcome variables. The methodological quality of each study was evaluated using recommended criteria. Ultimately, the review consisted of 51 articles.
UNASSIGNED: Physical examination results and noninvasive assessments of the optic nerve sheath diameter (ONSD) via sonography are positively associated with elevated ICP, and are employed as diagnostic and monitoring tools for elevated ICP in resource-limited settings. Management of elevated ICP necessitates an algorithmic approach that utilizes prophylactic measures and acute intervention treatments to mitigate the risk of secondary brain injury.
摘要：
■在不发达国家，创伤引起的死亡率和发病率更高，创伤性脑损伤（TBI）占所有创伤相关死亡的50％。颅内压升高（ICP）的发生，这是TBI病例中常见的病理生理现象，作为不利结果的促成因素。本系统综述的目的是分析重症监护病房中关于成人TBI升高ICP的管理的现有文献。尽管资源有限。
■本系统评价按照系统评价和荟萃分析方案的首选报告项目进行。搜索引擎，如PubMed,Cochrane数据库,和谷歌学者被用来找到高层次的证据，这将有助于形成合理的结论。
■总共确定了11.715篇文章，并根据预定标准和结果变量进行了单独评估，以确定其纳入或排除的资格。使用推荐的标准评估每个研究的方法学质量。最终,审查包括51篇文章。
■体格检查结果和通过超声检查对视神经鞘直径（ONSD）的非侵入性评估与ICP升高呈正相关，并在资源有限的环境中用作ICP升高的诊断和监测工具。升高的ICP的管理需要一种算法方法，该方法利用预防措施和急性干预治疗来减轻继发性脑损伤的风险。
■本系统评价按照系统评价和荟萃分析方案的首选报告项目进行。搜索引擎，如PubMed,Cochrane数据库,和谷歌学者被用来找到高层次的证据，这将有助于形成合理的结论。
■总共确定了11.715篇文章，并根据预定标准和结果变量进行了单独评估，以确定其纳入或排除的资格。使用推荐的标准评估每个研究的方法学质量。最终,审查包括51篇文章。
■体格检查结果和通过超声检查对视神经鞘直径（ONSD）的非侵入性评估与ICP升高呈正相关，并在资源有限的环境中用作ICP升高的诊断和监测工具。升高的ICP的管理需要一种算法方法，该方法利用预防措施和急性干预治疗来减轻继发性脑损伤的风险。
