关键词: Anatomopathology Antibacillary therapy Burkina Faso Ouagadougou Palatine tonsil Sub-Saharan Africa Tuberculosis

Mesh : Humans Palatine Tonsil / pathology Rifampin Isoniazid Tuberculosis, Miliary / drug therapy Burkina Faso Antitubercular Agents / therapeutic use

来  源:   DOI:10.48327/mtsi.v3i3.2023.422   PDF(Pubmed)

Abstract:
Tonsillar tuberculosis is the infectious localization of Koch\'s bacillus in the palatine tonsils. It is rare. Tonsillar tuberculosis associated with miliary tuberculosis is even more exceptional.
UNASSIGNED: The aim of our work is to report a rare case of tuberculous tonsillitis associated with miliary tuberculosis.
UNASSIGNED: This was a case of tonsillar tuberculosis associated with miliary tuberculosis. The main complaint was chronic odynophagia, which had been present for 7 months and was associated with weight loss. Questioning also revealed alcohol, tobacco and marijuana consumption.
UNASSIGNED: Oropharyngoscopy revealed an enlarged, ulcerated and hemorrhagic right tonsil, suggesting a malignant lesion. Diagnostic tonsillectomy with anatomopathological examination of the surgical specimen led to the diagnosis of tonsillar tuberculosis. A postoperative chest X-ray revealed tuberculous miliaria. No other tuberculosis site was identified. No other confirmatory biological tests were carried out. The patient was treated with 4 anti-tuberculosis drugs (rifampicin, isoniazid, pyrazinamide, ethambutol) during 2 months and 2 anti-tuberculosis drugs (Rifampicin, Isoniazid) during 4 months. The evolution was favorable and the patient was declared cured at the end of treatment. There was no recurrence after 5 years.
UNASSIGNED: Tonsillar tuberculosis is rare. Tonsillar tuberculosis associated with pulmonary miliaria is even more exceptional. Tonsil biopsy for anatomopathological examination is sufficient for diagnosis. A chest X-ray should be requested as part of the preoperative workup prior to any tonsillar biopsy or tonsillectomy. GeneXpert (MTB/RIF) should be carried out if possible, not only for its value in the biological confirmation of tuberculosis but also to identify rifampicin resistance. Antibacillary treatment often leads to a favorable outcome.
摘要:
扁桃体结核是科赫杆菌在腭扁桃体中的传染性定位。这是罕见的。扁桃体结核与粟粒性结核相关的情况更为特殊。
我们的工作的目的是报告一例罕见的结核性扁桃体炎与粟粒性结核相关的病例。
这是1例扁桃体结核与粟粒性结核相关的病例。主要主诉是慢性吞咽痛,这已经存在了7个月,并与体重减轻有关。询问还显示酒精,烟草和大麻消费。
口喉镜检查显示,溃疡和出血性右扁桃体,提示恶性病变.诊断性扁桃体切除术并对手术标本进行解剖病理学检查可诊断为扁桃体结核。术后胸部X线检查显示结核性miliaria。没有发现其他结核部位。没有进行其他验证性生物学测试。患者接受了4种抗结核药物(利福平,异烟肼,吡嗪酰胺,乙胺丁醇)在2个月内和2种抗结核药物(利福平,异烟肼)在4个月内。进展良好,患者在治疗结束时被宣布治愈。5年后无复发。
扁桃体结核是罕见的。与肺结核相关的扁桃体结核更为特殊。用于解剖病理学检查的扁桃体活检足以进行诊断。在任何扁桃体活检或扁桃体切除术之前,应要求进行胸部X光检查,作为术前检查的一部分。如果可能,应执行GeneXpert(MTB/RIF),不仅因为它在结核病的生物学确认中的价值,而且还鉴定利福平的耐药性。抗细菌治疗通常导致有利的结果。
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