PDF(Pubmed)
Abstract：
The traditional view of the aortic valve and aortic root as a simple conduit for blood flow between the left ventricle and the aorta is evolving with new insights from anatomy, physiology, cell biology, and advanced imaging techniques. This article provides an overview of the changing understanding of aortic root anatomy, shedding light on the intricate structures that contribute to maintaining unidirectional blood flow and the durability of the aortic valve. From historical perspectives to contemporary microscopic details, the components of the aortic root are explored, including the sinutubular junction, aortic sinuses, valve leaflets, and interleaflet triangles. Microscopically, the aortic annulus and leaflets reveal a complex architecture that facilitates blood flow while withstanding lifetime stresses. Additionally, the clinical relevance of aortic anatomy in surgical interventions is emphasized, highlighting the importance of preserving natural anatomy and physiology. A thorough understanding of the aortic root\'s complexity is crucial for optimizing therapeutic approaches and improving patient outcomes, paving the way for future advancements in aortic valve repair and regeneration techniques.
摘要：
主动脉瓣和主动脉根部作为左心室和主动脉之间的血液流动的简单管道的传统观点正在随着解剖学的新见解而发展。生理学,细胞生物学,和先进的成像技术。本文概述了对主动脉根部解剖结构的不断变化的理解，在复杂的结构上发光，有助于保持单向血流和主动脉瓣的耐久性。从历史的视角到当代的微观细节,探索主动脉根的组成部分，包括窦管交界处,主动脉窦,瓣膜小叶,和交织三角形。微观上,主动脉瓣环和小叶显示出复杂的结构，促进血液流动，同时承受终身压力。此外,强调了主动脉解剖在外科手术中的临床相关性，强调保持自然解剖学和生理学的重要性。彻底了解主动脉根部的复杂性对于优化治疗方法和改善患者预后至关重要。为未来主动脉瓣修复和再生技术的进步铺平了道路。
