PDF(Pubmed)
Abstract：
UNASSIGNED: Irradiation to treat head and neck cancer, causing chronic tissue damage, is associated with the development of vascular disease. Interest has risen over the effects of radiotherapy on major vessels, due to its high morbidity and mortality rate. However, small-vessel disease has been poorly studied and described.
UNASSIGNED: We present a case of a patient with bilateral necrosis of the anterior third of the tongue, occurring 3 years after chemoradiotherapy treatment for squamous cell carcinoma of the floor of the mouth. Contrast-enhanced CT scan showed multiple areas of stenosis concerning both external carotid arteries and their branches, and total opacification of lingual arteries. Conservative management was performed, with auto-amputation on the fifth day, which allowed healing by secondary intention.
UNASSIGNED: Necrosis of the tongue appears as a rare late complication of radiotherapy, possibly due to its acceleration effect on the atherosclerosis process. Following small-vessel disease, one can assume a higher potential risk of major-vessel disease, highlighting the importance of a routine assessment and prophylaxis of thrombotic events.
UNASSIGNED: We present a case of a patient with bilateral necrosis of the anterior third of the tongue, occurring 3 years after chemoradiotherapy treatment for squamous cell carcinoma of the floor of the mouth. Contrast-enhanced CT scan showed multiple areas of stenosis concerning both external carotid arteries and their branches, and total opacification of lingual arteries. Conservative management was performed, with auto-amputation on the fifth day, which allowed healing by secondary intention.
UNASSIGNED: Necrosis of the tongue appears as a rare late complication of radiotherapy, possibly due to its acceleration effect on the atherosclerosis process. Following small-vessel disease, one can assume a higher potential risk of major-vessel disease, highlighting the importance of a routine assessment and prophylaxis of thrombotic events.
摘要：
■照射治疗头颈癌，造成慢性组织损伤，与血管疾病的发展有关。人们对放疗对主要血管的影响越来越感兴趣，由于其高发病率和死亡率。然而,小血管疾病的研究和描述很少。
■我们介绍了一例双侧舌前三分之一坏死的患者，发生在口腔底鳞状细胞癌的放化疗治疗后3年。增强CT扫描显示多个狭窄区域，涉及颈外动脉及其分支，舌动脉完全混浊。进行保守管理，第五天自动截肢，允许通过次要意图治愈。
■舌坏死是一种罕见的晚期放疗并发症，可能是由于其对动脉粥样硬化过程的加速作用。小血管疾病之后,人们可以假设大血管疾病的潜在风险更高，强调常规评估和预防血栓形成事件的重要性。
■我们介绍了一例双侧舌前三分之一坏死的患者，发生在口腔底鳞状细胞癌的放化疗治疗后3年。增强CT扫描显示多个狭窄区域，涉及颈外动脉及其分支，舌动脉完全混浊。进行保守管理，第五天自动截肢，允许通过次要意图治愈。
■舌坏死是一种罕见的晚期放疗并发症，可能是由于其对动脉粥样硬化过程的加速作用。小血管疾病之后,人们可以假设大血管疾病的潜在风险更高，强调常规评估和预防血栓形成事件的重要性。
