关键词: Ellipsoids Fish Germinal centres Lymphoid tissues Melano-macrophage centres Spleen

Mesh : Animals Spleen Lymphoid Tissue Macrophages Fishes

来  源:   DOI:10.1016/j.fsi.2023.109280

Abstract:
In the present study, we review the structure and function of fish spleen with special emphasis on its condition in Elasmobranchs, Teleosts and Lungfish. Apart from the amount of splenic lymphoid tissue, the histological organization of the organ ensures the existence of areas involved in antigen trapping, the ellipsoids, and exhibit numerous melano-macrophages which appear isolated or forming the so-called melano-macrophage centres. An extensive discussion on the functional significance of these centres conclude that they are mere accumulations of macrophages consequence of tissue homeostasis rather than primitive germinal centres, as proposed by some authors.
摘要:
在本研究中,我们综述了鱼类脾脏的结构和功能,并特别强调了其在Elastmobranchs中的状况,硬骨鱼和龙鱼。除了脾淋巴组织的数量,器官的组织学组织确保了参与抗原捕获的区域的存在,椭圆体,并表现出许多黑体-巨噬细胞,它们似乎是孤立的或形成所谓的黑体-巨噬细胞中心。对这些中心功能意义的广泛讨论得出结论,它们仅仅是组织稳态而不是原始生发中心的巨噬细胞积累。正如一些作者提出的。
公众号