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Abstract：
The purpose of this study was to investigate the clinical utility of three-dimension (3D) high-resolution inversion recovery (IR)-prepared fast spoiled gradient-recalled (SPGR) magnetic resonance imaging (MRI) in the diagnosis of cranial nerve meningeal carcinomatosis (MC).
A total of 114 patients with MC from January 2015 to March 2020 were enrolled and their MRIs were analyzed retrospectively. All patients underwent MRIs before being administered a contrast agent. Both a 2D conventional MRI sequence and a 3D IR-prepared fast SPGR high-resolution T1-weighted (BRAVO) scan sequence were measured after contrast agent administration. The characteristics of MC and the involved cranial nerves were then examined.
Among the 114 MC patients, 81 (71.05%) had cranial nerve enhancement on contrast-enhanced 3D-BRAVO imaging, while only 41 (35.96%) had image enhancement on conventional MRI. The contrast-enhanced 3D-BRAVO displayed stronger image contrast enhancement of the cranial nerves than the conventional MRI (P < 0.001). Furthermore, detection rates for the facial and auditory nerves, trigeminal nerve, oculomotor nerve, sublingual nerve, optic nerve, glossopharyngeal/vagal/accessory nerve, and abductor nerve on contrast-enhanced 3D-BRAVO imaging were 58.77%, 47.37%, 9.65%, 8.77%, 5.26%, 3.51%, and 0.88%, respectively. We found a statistically significant difference between the affected facial and auditory nerves, as well as the trigeminal nerve, oculomotor nerve, sublingual nerve, and optic nerve.
In MC, contrast-enhanced 3D-BRAVO imaging displayed the cranial nerves more effectively than 2D conventional enhanced MRI. The facial, auditory, and trigeminal nerves are the primary nerves involved in MC, and improved scanning of these nerves would aid in the early detection and treatment of MC.
A total of 114 patients with MC from January 2015 to March 2020 were enrolled and their MRIs were analyzed retrospectively. All patients underwent MRIs before being administered a contrast agent. Both a 2D conventional MRI sequence and a 3D IR-prepared fast SPGR high-resolution T1-weighted (BRAVO) scan sequence were measured after contrast agent administration. The characteristics of MC and the involved cranial nerves were then examined.
Among the 114 MC patients, 81 (71.05%) had cranial nerve enhancement on contrast-enhanced 3D-BRAVO imaging, while only 41 (35.96%) had image enhancement on conventional MRI. The contrast-enhanced 3D-BRAVO displayed stronger image contrast enhancement of the cranial nerves than the conventional MRI (P < 0.001). Furthermore, detection rates for the facial and auditory nerves, trigeminal nerve, oculomotor nerve, sublingual nerve, optic nerve, glossopharyngeal/vagal/accessory nerve, and abductor nerve on contrast-enhanced 3D-BRAVO imaging were 58.77%, 47.37%, 9.65%, 8.77%, 5.26%, 3.51%, and 0.88%, respectively. We found a statistically significant difference between the affected facial and auditory nerves, as well as the trigeminal nerve, oculomotor nerve, sublingual nerve, and optic nerve.
In MC, contrast-enhanced 3D-BRAVO imaging displayed the cranial nerves more effectively than 2D conventional enhanced MRI. The facial, auditory, and trigeminal nerves are the primary nerves involved in MC, and improved scanning of these nerves would aid in the early detection and treatment of MC.
摘要：
目的：本研究的目的是探讨三维（3D）高分辨率反转恢复（IR）制备的快速破坏梯度回忆（SPGR）磁共振成像（MRI）在颅神经脑膜癌（MC）诊断中的临床应用。
方法：纳入2015年1月至2020年3月的114例MC患者，对其MRI进行回顾性分析。所有患者在接受造影剂之前都进行了MRI检查。在施用造影剂后，测量了2D常规MRI序列和3DIR制备的快速SPGR高分辨率T1加权（BRAVO）扫描序列。然后检查MC的特征和受累的颅神经。
结果：在114例MC患者中，81例（71.05%）在对比增强3D-BRAVO成像上有颅神经增强，只有41例(35.96%)在常规MRI上有图像增强。对比增强的3D-BRAVO显示出比常规MRI更强的颅神经图像对比度增强（P<0.001）。此外，面神经和听觉神经的检测率，三叉神经,动眼神经,舌下神经,视神经,舌咽/迷走神经/副神经，对比增强3D-BRAVO成像显示外展神经占58.77%,47.37%,9.65%,8.77%,5.26%,3.51%,和0.88%，分别。我们发现受影响的面部和听觉神经之间存在统计学上的显着差异，以及三叉神经，动眼神经,舌下神经,和视神经.
结论：在MC中，对比增强3D-BRAVO成像比2D常规增强MRI更有效地显示颅神经。面部，听觉,三叉神经是涉及MC的主要神经，和改善这些神经的扫描将有助于早期发现和治疗MC。
方法：纳入2015年1月至2020年3月的114例MC患者，对其MRI进行回顾性分析。所有患者在接受造影剂之前都进行了MRI检查。在施用造影剂后，测量了2D常规MRI序列和3DIR制备的快速SPGR高分辨率T1加权（BRAVO）扫描序列。然后检查MC的特征和受累的颅神经。
结果：在114例MC患者中，81例（71.05%）在对比增强3D-BRAVO成像上有颅神经增强，只有41例(35.96%)在常规MRI上有图像增强。对比增强的3D-BRAVO显示出比常规MRI更强的颅神经图像对比度增强（P<0.001）。此外，面神经和听觉神经的检测率，三叉神经,动眼神经,舌下神经,视神经,舌咽/迷走神经/副神经，对比增强3D-BRAVO成像显示外展神经占58.77%,47.37%,9.65%,8.77%,5.26%,3.51%,和0.88%，分别。我们发现受影响的面部和听觉神经之间存在统计学上的显着差异，以及三叉神经，动眼神经,舌下神经,和视神经.
结论：在MC中，对比增强3D-BRAVO成像比2D常规增强MRI更有效地显示颅神经。面部，听觉,三叉神经是涉及MC的主要神经，和改善这些神经的扫描将有助于早期发现和治疗MC。
