关键词: OOPE cost of illness economic burden mosquito-borne diseases out-of-pocket expenditure vector-borne diseases

来  源:   DOI:10.2196/50985   PDF(Pubmed)

Abstract:
BACKGROUND: Globally, among all the vector-borne diseases, mosquito-borne diseases are responsible for a substantial number of cases and deaths and amount to an economic cost of US $12 billion per year. However, there is a dearth of systematic research conducted on the economic burden of mosquito-borne diseases. To address the lack of comprehensive information on this topic, a systematic review will be conducted to synthesize evidence for informing targeted policies and strategies addressing this growing burden and for better financial protection of households.
OBJECTIVE: The systematic review aims to review the economic burden of mosquito-borne diseases in low- and middle-income countries (LMICs). The review estimates the total cost, which is the compilation of both the direct costs and indirect costs. Additionally, it reports cost estimates per disease, country, and patient. The review outcome will also discuss the impact of the economic burden in terms of out-of-pocket expenditure, catastrophic health expenditure, impoverishment, and gross domestic product impact due to mosquito-borne diseases in LMICs.
METHODS: Systematic searches will be conducted in PubMed (MEDLINE), Ovid Embase, Scopus, the cumulative index of nursing and allied health literacy, and Cochrane CENTRAL. Additionally, websites of the World Bank, World Health Organization, and Asian Development Bank as well as grey literature (eg, Malaria No More and the Ministry of Health websites) will be searched to gather comprehensive information on the topic and identify studies published in the English language. The titles and abstracts will be independently screened by 2 reviewers, followed by a full-text review against the inclusion criteria. Disagreements will be resolved through discussion with a third author. The methodological reporting quality of the studies will be evaluated using the Larg and Moss checklist, Cochrane risk-of-bias tool for randomized trials, and the Consensus on Health Economic Criteria. Data will be extracted using a standardized data extraction form.
RESULTS: The protocol was registered in PROSPERO (CRD42023427111) prior to the initiation of the search strategy. The review is currently ongoing and will synthesize information from the identified studies through a process involving structured screening, data extraction, and critical appraisal in the form of tables and a narrative summary of studies reporting the economic burden incurred due to mosquito-borne diseases in LMICs.
CONCLUSIONS: This review seeks to report the economic burden of mosquito-borne diseases. It will act as evidence for policymakers to prioritize their decisions regarding containing the prevalence of mosquito-borne diseases and the means to lowering the incidence of diseases spread by mosquitoes.
BACKGROUND: PROSPERO CRD42023427111; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=427111.
UNASSIGNED: PRR1-10.2196/50985.
摘要:
背景:在全球范围内,在所有媒介传播疾病中,蚊媒疾病是造成大量病例和死亡的原因,每年造成120亿美元的经济损失。然而,缺乏对蚊媒疾病经济负担的系统研究。为了解决缺乏关于这一主题的全面信息的问题,将进行系统审查,以综合证据,为解决这一日益增加的负担的有针对性的政策和战略提供信息,并为家庭提供更好的财政保护。
目的:系统评价旨在回顾中低收入国家(LMICs)蚊媒疾病的经济负担。审查估计了总成本,这是直接成本和间接成本的汇编。此外,它报告了每种疾病的成本估算,国家,和病人。检讨结果亦会讨论经济负担对自费开支的影响,灾难性的卫生支出,贫困,以及中低收入国家蚊媒疾病对国内生产总值的影响。
方法:系统搜索将在PubMed(MEDLINE)中进行,OvidEmbase,Scopus,护理和相关健康素养的累积指数,和科克伦中央。此外,世界银行的网站,世界卫生组织,和亚洲开发银行以及灰色文献(例如,将搜索MalariaNoMore和卫生部网站),以收集有关该主题的全面信息,并确定以英语发表的研究。标题和摘要将由两名审稿人独立筛选,然后根据纳入标准进行全文审查。分歧将通过与第三作者的讨论来解决。将使用Larg和Moss清单评估研究的方法学报告质量,用于随机试验的Cochrane偏见风险工具,以及《卫生经济标准共识》。将使用标准化的数据提取表格来提取数据。
结果:在启动搜索策略之前,该方案已在PROSPERO(CRD42023427111)中注册。审查目前正在进行中,并将通过涉及结构化筛选的过程来综合已确定研究的信息,数据提取,以及以表格和叙述性总结的形式进行的批判性评估,这些研究报告了中低收入国家因蚊媒疾病而造成的经济负担。
结论:本综述旨在报告蚊媒疾病的经济负担。它将为决策者提供证据,以优先考虑其关于控制蚊子传播疾病流行率和降低蚊子传播疾病发病率的手段的决定。
背景:PROSPEROCRD42023427111;https://www.crd.约克。AC.uk/prospro/display_record.php?RecordID=427111。
PRR1-10.2196/50985。
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