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Abstract：
Background Rectal resection with total mesorectal excision is a difficult surgery with potential risks of complications. This study aims to assess the quality of life (QoL) of patients with low rectal cancer who have bowel function disorders equivalent to major low anterior resection syndrome (LARS) and its risk factors before treatment. Methods A descriptive cross-sectional study was conducted on 83 patients diagnosed with low rectal cancer who had not been treated. Quality of life was assessed by the European Organisation for Research and Treatment of Cancer\'s (EORTC) 30-Item Core Quality of Life Questionnaire (QLQ-C30) and the LARS scale. Results Fiffty-five (66.3%) patients had moderate/major low anterior resection syndrome, of which 34 (41%) patients had major low anterior resection syndrome. The study implicated that old age, smoking, and alcohol consumption were risk factors associated with high scores on the scale for LARS (p<0.05). Patients with low rectal cancer had low overall QoL score. In the symptom area of increased financial hardship scores, factors that adversely affected the poor quality of life in patients with low rectal cancer were fatigue and bowel dysfunction with p<0.05. Conclusion The percentage of rectal cancer patients with low anterior resection syndrome was high, and the associated risk factors were old age, smoking, and drinking alcohol. Before treatment, the physical and mental health of patients with low rectal cancer with major low anterior resection syndrome was very poor.
摘要：
背景直肠全直肠系膜切除术是一种困难的手术，具有潜在的并发症风险。这项研究旨在评估低位直肠癌患者的生活质量（QoL），这些患者的肠功能障碍等同于主要低位前切除综合征（LARS）及其治疗前的危险因素。方法对83例未经治疗的低位直肠癌患者进行描述性横断面研究。通过欧洲癌症研究与治疗组织（EORTC）30项核心生活质量问卷（QLQ-C30）和LARS量表评估生活质量。结果Fiffty-5例(66.3%)患者存在中/大低位前切除综合征,其中34例（41％）患者患有严重的低位前切除综合征。这项研究暗示了老年，吸烟,和饮酒是与LARS量表得分高相关的危险因素(p<0.05)。低位直肠癌患者的总体QoL评分较低。在经济困难分数增加的症状领域，影响低位直肠癌患者生活质量差的因素为疲乏和肠功能障碍,p<0.05。结论低位前切除综合征的直肠癌患者比例较高,相关的危险因素是年龄，吸烟,和饮酒。治疗前,低位直肠癌合并低位前切除综合征患者的身心健康状况较差。
