PDF(Pubmed)
Abstract：
UNASSIGNED: Periodontitis is a chronic infectious disease affecting periodontium having multifactorial etiology, can cause significant systemic challengein addition to localized inflammation, tissue damage, and bone resorption. A serological marker of systemic inflammation known as C-reactive protein has been linked to an increased risk for a number of pathological conditions, including cardiovascular diseases.
UNASSIGNED: To estimate levels of serum C-reactive protein in healthy individuals and subjects with periodontal diseases and to compare serum C-reactive protein levels in subjects having periodontal disease pre-operatively & post-operatively.
UNASSIGNED: The study was conducted on 60 subjects age ranging from 35 to 60 years. 30 individuals with healthy periodontium were in group 1 (control group) and the remaining 30 were diagnosed as adult periodontitis were in group 2 (experimental group). Periodontal examination done using gingival index, plaque index, periodontal pocket depth, and Russel\'s index. CRP levels were examined between group 1 and group 2 and in group 2 between baseline visit before treatment and 2 months after treatment.
UNASSIGNED: The findings of this study show a significant connection between periodontal disease and the inflammatory marker CRP in the body, as well as a tendency for a significant decrease in serumCRP levels following periodontitis therapy. At baseline, there was a positive correlation among C-reactive protein, probing pocket depth, and Russell\'s index.
UNASSIGNED: As CRP is a key mediator for cardiovascular disease, an increase in C- reactive protein levels in periodontal diseases suggests a significant connection between periodontitis and cardiovascular diseases. Early periodontal treatment might decrease the severity of cardiovascular disease that already exists. This suggests that periodontal examination should be part of routine practicealong with cardiovascular examination.
UNASSIGNED: To estimate levels of serum C-reactive protein in healthy individuals and subjects with periodontal diseases and to compare serum C-reactive protein levels in subjects having periodontal disease pre-operatively & post-operatively.
UNASSIGNED: The study was conducted on 60 subjects age ranging from 35 to 60 years. 30 individuals with healthy periodontium were in group 1 (control group) and the remaining 30 were diagnosed as adult periodontitis were in group 2 (experimental group). Periodontal examination done using gingival index, plaque index, periodontal pocket depth, and Russel\'s index. CRP levels were examined between group 1 and group 2 and in group 2 between baseline visit before treatment and 2 months after treatment.
UNASSIGNED: The findings of this study show a significant connection between periodontal disease and the inflammatory marker CRP in the body, as well as a tendency for a significant decrease in serumCRP levels following periodontitis therapy. At baseline, there was a positive correlation among C-reactive protein, probing pocket depth, and Russell\'s index.
UNASSIGNED: As CRP is a key mediator for cardiovascular disease, an increase in C- reactive protein levels in periodontal diseases suggests a significant connection between periodontitis and cardiovascular diseases. Early periodontal treatment might decrease the severity of cardiovascular disease that already exists. This suggests that periodontal examination should be part of routine practicealong with cardiovascular examination.
摘要：
■牙周炎是一种影响牙周组织的慢性感染性疾病，具有多因素病因，除了局部炎症，组织损伤,和骨吸收。一种称为C反应蛋白的全身性炎症的血清学标志物与许多病理状况的风险增加有关。包括心血管疾病.
评估健康个体和患有牙周疾病的受试者的血清C-反应蛋白水平,并比较患有牙周疾病的受试者术前和术后的血清C-反应蛋白水平。
■该研究对年龄在35至60岁之间的60名受试者进行。健康牙周炎者30例为第1组(对照组),诊断为成人牙周炎者30例为第2组(实验组)。使用牙龈指数进行牙周检查，菌斑指数,牙周袋深度，和罗素指数。在治疗前和治疗后2个月的基线访视之间，检测第1组和第2组之间以及第2组之间的CRP水平。
■这项研究的结果表明，牙周病与体内炎症标志物CRP之间存在显着联系，以及牙周炎治疗后血清CRP水平显着下降的趋势。在基线,C反应蛋白之间呈正相关，探测袋深度,和罗素指数。
■由于CRP是心血管疾病的关键介质，牙周疾病中C-反应蛋白水平升高提示牙周炎与心血管疾病之间存在显著联系.早期牙周治疗可能会降低已经存在的心血管疾病的严重程度。这表明牙周检查应与心血管检查一起成为常规实践的一部分。
评估健康个体和患有牙周疾病的受试者的血清C-反应蛋白水平,并比较患有牙周疾病的受试者术前和术后的血清C-反应蛋白水平。
■该研究对年龄在35至60岁之间的60名受试者进行。健康牙周炎者30例为第1组(对照组),诊断为成人牙周炎者30例为第2组(实验组)。使用牙龈指数进行牙周检查，菌斑指数,牙周袋深度，和罗素指数。在治疗前和治疗后2个月的基线访视之间，检测第1组和第2组之间以及第2组之间的CRP水平。
■这项研究的结果表明，牙周病与体内炎症标志物CRP之间存在显着联系，以及牙周炎治疗后血清CRP水平显着下降的趋势。在基线,C反应蛋白之间呈正相关，探测袋深度,和罗素指数。
■由于CRP是心血管疾病的关键介质，牙周疾病中C-反应蛋白水平升高提示牙周炎与心血管疾病之间存在显著联系.早期牙周治疗可能会降低已经存在的心血管疾病的严重程度。这表明牙周检查应与心血管检查一起成为常规实践的一部分。
