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Abstract：
Chronic wounds arising from accidents, surgeries, or diseases impose a significant clinical and economic burden, underscoring the need for effective solutions to prevent severe complications. Recent advancements in materials science and electrochemical technology have facilitated the development of conformable electrochemical platforms for detection and management, incorporating monitoring, diagnosis, and treatment. Nevertheless, current wound detection and therapy systems face challenges related to the stability and specificity of sensor monitoring, as well as the need for on-site and comprehensive evaluation criteria to offer timely treatment guidance and follow-up care. This review provides a comprehensive overview of the closed-loop management system, emphasizing wound biomarker detection, wound assessment, and on-demand treatment, ultimately culminating in an integrated wound management approach by conformable electrochemical devices. Additionally, we explore the challenges, opportunities, and future prospects of soft and stretchable electrochemical biosensors, with the aim of enhancing the efficiency and timeliness of wound management.
摘要：
事故引起的慢性伤口，手术,或疾病造成重大的临床和经济负担，强调需要有效的解决方案来预防严重的并发症。材料科学和电化学技术的最新进展促进了用于检测和管理的一致电化学平台的发展，纳入监测，诊断,和治疗。然而，当前的伤口检测和治疗系统面临与传感器监测的稳定性和特异性相关的挑战，以及需要现场和全面的评估标准，以提供及时的治疗指导和后续护理。这篇综述全面概述了闭环管理系统,强调伤口生物标志物检测，伤口评估,和按需治疗，最终通过一致的电化学装置形成综合的伤口管理方法。此外,我们探索挑战，机遇,以及柔性和可拉伸电化学生物传感器的未来前景，目的是提高伤口管理的效率和及时性。
