PDF(Pubmed)
Abstract：
Components in blood play an important role in wound healing and subsequent tissue regeneration processes. The fibrin matrix and various bioactive molecules work together to participate in this complex yet vital biological process. As a means of personalized medicine, autologous platelet concentrates have become an integral part of various tissue regeneration strategies. Here, we focus on how autologous platelet concentrates play a role in each stage of tissue healing, as well as how they work in conjunction with different types of biomaterials to participate in this process. In particular, we highlight the use of various biomaterials to protect, deliver and enhance these libraries of biomolecules, thereby overcoming the inherent disadvantages of autologous platelet concentrates and enabling them to function better in tissue regeneration.
摘要：
血液中的成分在伤口愈合和随后的组织再生过程中起重要作用。纤维蛋白基质和各种生物活性分子共同参与这一复杂但至关重要的生物过程。作为个性化医疗的一种手段，自体血小板浓缩物已成为各种组织再生策略中不可或缺的一部分.这里,我们专注于自体血小板浓缩物如何在组织愈合的每个阶段发挥作用，以及它们如何与不同类型的生物材料一起参与这一过程。特别是,我们强调使用各种生物材料来保护，提供和增强这些生物分子库，从而克服了自体血小板浓缩物的固有缺点并使其在组织再生中更好地发挥作用。
