PDF(Pubmed)
Abstract：
UNASSIGNED: Micro-invasive glaucoma surgery involves a group of treatment methods associated with a low rate of side effects and good effectiveness outcomes. One of the most frequently performed procedures belonging to this group is iStent microstent implantation. The aim of this study was to perform a retrospective evaluation of the safety and efficacy of a combined procedure involving cataract phacoemulsification and single iStent microstent implantation, performed simultaneously.
UNASSIGNED: The complete medical records of 62 patients (91 eyes) were analyzed retrospectively, including the best corrected visual acuity, intraocular pressure, the mean defect of visual fields, and the number of active substances used in eye drops. The follow-up times were 1, 3, 6, 9, and 12 months after the surgical procedure.
UNASSIGNED: A significant improvement in the best corrected visual acuity and a reduction of the intraocular pressure were achieved after the surgery. On average, after 12 months, the best corrected visual acuity improved from 0.70 (0.25) to 0.91 (0.18; p = 0.001), the intraocular pressure reduced from 17.76 (3.95) to 14.91 (3.04; p = 0.0001), and the number of active substances used in eye drops reduced from 2.07 (1.08) to 0.70 (0.06; p = 0001). In addition, we found that patients who initially showed higher intraocular pressure values did not benefit from surgery in the aspect of the number of active substances used in their eye drops. Intraoperative and postoperative adverse events were transient and ultimately did not affect the outcomes.
UNASSIGNED: Simultaneous cataract phacoemulsification with single iStent implantation in patients with open-angle glaucoma is a safe and effective method for reducing intraocular pressure and the number of topical medications that must be used. Having initially higher intraocular pressure values may limit the beneficial effects of iStent implantation by subordinating patients from topical treatment; thus, single iStent implantation may not be the most favorable choice in uncontrolled glaucoma cases.
UNASSIGNED: The complete medical records of 62 patients (91 eyes) were analyzed retrospectively, including the best corrected visual acuity, intraocular pressure, the mean defect of visual fields, and the number of active substances used in eye drops. The follow-up times were 1, 3, 6, 9, and 12 months after the surgical procedure.
UNASSIGNED: A significant improvement in the best corrected visual acuity and a reduction of the intraocular pressure were achieved after the surgery. On average, after 12 months, the best corrected visual acuity improved from 0.70 (0.25) to 0.91 (0.18; p = 0.001), the intraocular pressure reduced from 17.76 (3.95) to 14.91 (3.04; p = 0.0001), and the number of active substances used in eye drops reduced from 2.07 (1.08) to 0.70 (0.06; p = 0001). In addition, we found that patients who initially showed higher intraocular pressure values did not benefit from surgery in the aspect of the number of active substances used in their eye drops. Intraoperative and postoperative adverse events were transient and ultimately did not affect the outcomes.
UNASSIGNED: Simultaneous cataract phacoemulsification with single iStent implantation in patients with open-angle glaucoma is a safe and effective method for reducing intraocular pressure and the number of topical medications that must be used. Having initially higher intraocular pressure values may limit the beneficial effects of iStent implantation by subordinating patients from topical treatment; thus, single iStent implantation may not be the most favorable choice in uncontrolled glaucoma cases.
摘要：
■微侵袭性青光眼手术涉及一组与副作用发生率低和效果好相关的治疗方法。属于该组的最频繁执行的程序之一是iStent微支架植入。这项研究的目的是对涉及白内障超声乳化和单iStent微支架植入的联合手术的安全性和有效性进行回顾性评估。同时进行。
■回顾性分析了62例患者（91只眼）的完整病历，包括最好的矫正视力，眼内压,视野的平均缺陷，以及滴眼液中使用的活性物质的数量。随访时间分别为手术后1、3、6、9和12个月。
■手术后实现了最佳矫正视力的显着改善和眼内压的降低。平均而言,12个月后,最佳矫正视力从0.70（0.25）提高到0.91（0.18；p=0.001），眼压从17.76（3.95）降至14.91（3.04；p=0.0001），滴眼液中使用的活性物质的数量从2.07（1.08）减少到0.70（0.06；p=0001）。此外,我们发现，最初显示较高眼压值的患者在滴眼液中使用的活性物质数量方面没有从手术中受益。术中和术后不良事件是短暂的，最终不影响结果。
■开角型青光眼患者同时行白内障超声乳化吸除联合单iStent植入术是一种安全有效的方法，可降低眼压和减少必须使用的局部用药数量。最初具有较高的眼压值可能会限制局部治疗从属患者的iStent植入的有益效果；因此，在未控制的青光眼病例中,单支架植入术可能不是最有利的选择。
■回顾性分析了62例患者（91只眼）的完整病历，包括最好的矫正视力，眼内压,视野的平均缺陷，以及滴眼液中使用的活性物质的数量。随访时间分别为手术后1、3、6、9和12个月。
■手术后实现了最佳矫正视力的显着改善和眼内压的降低。平均而言,12个月后,最佳矫正视力从0.70（0.25）提高到0.91（0.18；p=0.001），眼压从17.76（3.95）降至14.91（3.04；p=0.0001），滴眼液中使用的活性物质的数量从2.07（1.08）减少到0.70（0.06；p=0001）。此外,我们发现，最初显示较高眼压值的患者在滴眼液中使用的活性物质数量方面没有从手术中受益。术中和术后不良事件是短暂的，最终不影响结果。
■开角型青光眼患者同时行白内障超声乳化吸除联合单iStent植入术是一种安全有效的方法，可降低眼压和减少必须使用的局部用药数量。最初具有较高的眼压值可能会限制局部治疗从属患者的iStent植入的有益效果；因此，在未控制的青光眼病例中,单支架植入术可能不是最有利的选择。
