PDF(Pubmed)
Abstract：
UNASSIGNED: Most of abortions occur before the 13th week of pregnancy. Nowadays, non-surgical approaches for evacuation of uterine have been replaced with surgical ones due to the reduction in bleeding, fewer complications, ease of management, and cost-effectiveness. Misoprostol is a prostaglandin E1 analog that is used for labor induction. It is known as a safe drug with very few side effects.
UNASSIGNED: A 29-year-old woman with the gestational age of 11 weeks and 6 days with a diagnosis of cystic hygroma introduced herself to the labor ward. At the time of hospitalization, the patient was conscious. The heart sounds were normal. A vaginal exam indicated no pathological findings. Totally, she received 1000 mg of Misoprostol. Approximately, 2 hours after the last placement of Misoprostol, the patient developed bending and mild cyanosis of fingers and showed tachycardia with a pulse rate of 140 beats/min. Her O2 saturation decreased to 78%. At this time, the patient had a successful miscarriage. Echocardiography showed an ejection fraction of 55% and normal right ventricular size. The electrocardiogram showed sinus tachycardia. Therefore, she was sent to CCU with a possible diagnosis of embolism. The cardiologist administered a heparin drip of 5000-unit IV stat, and 1000 unit/h heparin and asked for a D-Dimer test. However, the laboratory reported that the patient\'s blood sample was hemolyzed and they could only check her hemoglobin which was 4 g/dl. Immediately, the heparin drip was held and the patient received 3 packed cells. Her Hb was 6.5 g/dl. 12 hours later she showed tachycardia, and her O2 saturation reduced to 70%. She lost her consciousness. Nearly 40 minutes later, she had cardiorespiratory arrest and CPR wasn\'t successful and she died.
UNASSIGNED: In Conclusion, even a frequently used drug such as Misoprostol can cause life-threatening side effects, leading to emergent situations.
UNASSIGNED: A 29-year-old woman with the gestational age of 11 weeks and 6 days with a diagnosis of cystic hygroma introduced herself to the labor ward. At the time of hospitalization, the patient was conscious. The heart sounds were normal. A vaginal exam indicated no pathological findings. Totally, she received 1000 mg of Misoprostol. Approximately, 2 hours after the last placement of Misoprostol, the patient developed bending and mild cyanosis of fingers and showed tachycardia with a pulse rate of 140 beats/min. Her O2 saturation decreased to 78%. At this time, the patient had a successful miscarriage. Echocardiography showed an ejection fraction of 55% and normal right ventricular size. The electrocardiogram showed sinus tachycardia. Therefore, she was sent to CCU with a possible diagnosis of embolism. The cardiologist administered a heparin drip of 5000-unit IV stat, and 1000 unit/h heparin and asked for a D-Dimer test. However, the laboratory reported that the patient\'s blood sample was hemolyzed and they could only check her hemoglobin which was 4 g/dl. Immediately, the heparin drip was held and the patient received 3 packed cells. Her Hb was 6.5 g/dl. 12 hours later she showed tachycardia, and her O2 saturation reduced to 70%. She lost her consciousness. Nearly 40 minutes later, she had cardiorespiratory arrest and CPR wasn\'t successful and she died.
UNASSIGNED: In Conclusion, even a frequently used drug such as Misoprostol can cause life-threatening side effects, leading to emergent situations.
摘要：
■大多数流产发生在怀孕第13周之前。如今,由于出血减少，子宫的非手术方法已被手术方法取代，并发症少,易于管理，和成本效益。米索前列醇是用于引产的前列腺素E1类似物。它被认为是一种安全的药物，副作用很少。
■一名29岁的妇女，胎龄为11周零6天，诊断为囊性水瘤，她向分娩病房介绍了自己。在住院的时候，病人是有意识的。心音正常。阴道检查未发现病理结果。完全正确,她接受了1000毫克米索前列醇.大约,最后一次放置米索前列醇2小时后，患者出现手指弯曲和轻度紫癜，并表现为心动过速，脉搏率为140次/分钟。她的O2饱和度下降到78%。此时,病人流产成功。超声心动图显示射血分数为55％，右心室大小正常。心电图显示窦性心动过速。因此,她被送往CCU,可能诊断为栓塞.心脏病专家给肝素滴注了5000单位的静脉注射，和1000单位/小时肝素，并要求进行D-二聚体测试。然而,实验室报告说，患者的血液样本被溶血，他们只能检查她的血红蛋白为4g/dl。立刻,保持肝素滴注，患者接受3个包装细胞。她的Hb为6.5g/dl。12小时后她出现了心动过速,她的氧气饱和度降低到70%.她失去了她的意识。将近40分钟后,她有心肺呼吸骤停和心肺复苏没有成功，她死了。
■在结论中，即使是经常使用的药物如米索前列醇也会引起危及生命的副作用，导致紧急情况。
■一名29岁的妇女，胎龄为11周零6天，诊断为囊性水瘤，她向分娩病房介绍了自己。在住院的时候，病人是有意识的。心音正常。阴道检查未发现病理结果。完全正确,她接受了1000毫克米索前列醇.大约,最后一次放置米索前列醇2小时后，患者出现手指弯曲和轻度紫癜，并表现为心动过速，脉搏率为140次/分钟。她的O2饱和度下降到78%。此时,病人流产成功。超声心动图显示射血分数为55％，右心室大小正常。心电图显示窦性心动过速。因此,她被送往CCU,可能诊断为栓塞.心脏病专家给肝素滴注了5000单位的静脉注射，和1000单位/小时肝素，并要求进行D-二聚体测试。然而,实验室报告说，患者的血液样本被溶血，他们只能检查她的血红蛋白为4g/dl。立刻,保持肝素滴注，患者接受3个包装细胞。她的Hb为6.5g/dl。12小时后她出现了心动过速,她的氧气饱和度降低到70%.她失去了她的意识。将近40分钟后,她有心肺呼吸骤停和心肺复苏没有成功，她死了。
■在结论中，即使是经常使用的药物如米索前列醇也会引起危及生命的副作用，导致紧急情况。
