PDF(Pubmed)
Abstract：
BACKGROUND: Penile cancer (PC) is a highly aggressive disease, with a significant tendency for lymphatic spreading and subsequent development of distant metastases. The mutilating nature of PC surgical treatment has profound implications on the patient\'s body integrity and self-image, sexual life and intimacy, voiding and mental health. The aim of our study was to comprehensively evaluate PC patients\' post-treatment quality of life (QoL), sexual activity, self-esteem, fatigue and fear of disease recurrence. (2) Methods: A cross-sectional study was conducted at the Clinic of Urology, University Clinical Centre of Serbia, and included 31 PC patients. Data were collected by means of a questionnaire. (3) Results: The average score on the Global health status scale was 67.2 out of 100 (ranging from 16.7 to 100), and the SD was 22.5. Hierarchical linear regression analysis showed that demographic characteristics, Hospital Anxiety and Depression scale (HADS) anxiety and depression scores, total Multidimensional Fatigue Inventory, Fear of cancer recurrence and Rosenberg scores and erectile function score explained a total of 78.2% of the variance in the global health status/QoL scale of PC patients. (4) Conclusions: Efforts should be made not only to increase the survival of PC patients after surgical treatment but also to enable the best possible level of QoL in the post-operative period.
摘要：
背景：阴茎癌（PC）是一种高度侵袭性的疾病，具有明显的淋巴扩散趋势和随后的远处转移的发展。PC手术治疗的致残性对患者的身体完整性和自我形象具有深远的影响,性生活和亲密关系，排尿和心理健康。我们研究的目的是全面评估PC患者治疗后的生活质量(QoL)，性活动,自尊,疲劳和害怕疾病复发。（2）方法：在泌尿外科诊所进行横断面研究，塞尔维亚大学临床中心，包括31名PC患者。通过问卷收集数据。（3）结果：全球健康状况量表的平均得分为67.2分（100分）（16.7至100分），SD为22.5。分层线性回归分析表明,人口学特征,医院焦虑抑郁量表(HADS)焦虑抑郁评分,多维疲劳总清单，对癌症复发的恐惧以及Rosenberg评分和勃起功能评分解释了PC患者的全球健康状况/QoL量表差异的78.2％。（4）结论：不仅应努力增加手术治疗后PC患者的生存率，而且还应确保术后QoL达到最佳水平。
