Abstract：
In India the cancer burden for 2021 was 26.7 million disability-adjusted life years (DALYs), and this is expected to increase to 29.8 million in 2025 (Kulothungan et al., 2022). According to the World Health Organisation (WHO), cancer is a leading cause of death worldwide, accounting for one in six deaths. As per WHO, palliative care is a strategy that assists both adults and children along with their families in dealing with life-threatening illnesses. Currently, only 14% of those in need of pain and palliative (P&P) care receive it globally (WHO, 2020). Financial toxicity (FT) is the term used to describe the negative effects that an excessive financial burden resulting from cancer have on patients, their families, and society (Desai and Gyawali, 2020). Addressing this gap will require significant adjustments to both demand- and supply-side policies to ensure accessible and equitable cancer care in India (Caduff et al., 2019). Measuring FT along with health-related quality of life (HRQoL) represents a clinically relevant and patient-centred approach (de Souza et al., 2017).
OBJECTIVE: To estimate FT and its association with quality of life (QoL).
METHODS: This was an observational descriptive study conducted among cancer patients recommended for P&P care. Scores were estimated from September 2022 to February 2023 using official tools: the Functional Assessment for Chronic illness Treatment Compressive Score for Financial Toxicity (FACIT-COST) and the European Organisation for Research and Treatment of Cancer (EORTC) Quality of life Questionnaires for Cancer (QLQ30).
RESULTS: From 150 patients (70 males and 80 females, mean age 54.96 ± 13.5 years), 92.6% suffered from FT. Eleven patients (7.3%) were under FT grade 0, 41 (27.3%) were FT grade 1, 98 (65.3%) were FT grade 2, and no patients were under FT grade 3. At criterial alpha 0.05 (95%CI), FT and the global score for HRQoL showed an association. Among inpatient department (IPD) expenses, medication bills contributed the greatest expense at 33%, and among outpatient department (OPD) expenses treatment expenses contributed 50% of the total. Breast cancer (30 cases, 20%) and oral cancer (26 cases, 17.3%) were the most frequent cancers.
CONCLUSIONS: FT measured using the COST tool showed an association with HRQoL.
UNASSIGNED: This paper refers to the insurance policies available for cancer patients irrespective of P&P care treatment.
OBJECTIVE: To estimate FT and its association with quality of life (QoL).
METHODS: This was an observational descriptive study conducted among cancer patients recommended for P&P care. Scores were estimated from September 2022 to February 2023 using official tools: the Functional Assessment for Chronic illness Treatment Compressive Score for Financial Toxicity (FACIT-COST) and the European Organisation for Research and Treatment of Cancer (EORTC) Quality of life Questionnaires for Cancer (QLQ30).
RESULTS: From 150 patients (70 males and 80 females, mean age 54.96 ± 13.5 years), 92.6% suffered from FT. Eleven patients (7.3%) were under FT grade 0, 41 (27.3%) were FT grade 1, 98 (65.3%) were FT grade 2, and no patients were under FT grade 3. At criterial alpha 0.05 (95%CI), FT and the global score for HRQoL showed an association. Among inpatient department (IPD) expenses, medication bills contributed the greatest expense at 33%, and among outpatient department (OPD) expenses treatment expenses contributed 50% of the total. Breast cancer (30 cases, 20%) and oral cancer (26 cases, 17.3%) were the most frequent cancers.
CONCLUSIONS: FT measured using the COST tool showed an association with HRQoL.
UNASSIGNED: This paper refers to the insurance policies available for cancer patients irrespective of P&P care treatment.
摘要：
在印度，2021年的癌症负担为2670万残疾调整寿命年(DALYs)。预计到2025年将增加到2980万(Kulothungan等人。,2022年）。根据世界卫生组织（WHO）癌症是全球死亡的主要原因，占六分之一的死亡人数。根据世卫组织，姑息治疗是一种策略，可帮助成人和儿童及其家人应对危及生命的疾病。目前,在全球范围内，只有14%的需要疼痛和姑息治疗(P&P)的人接受了这种治疗(世卫组织，2020）。金融毒性（FT）是用于描述癌症导致的过度经济负担对患者的负面影响的术语，他们的家人,和社会(德赛和嘉瓦利，2020）。解决这一差距将需要对需求和供应方政策进行重大调整，以确保印度可获得和公平的癌症护理（Caduff等人。,2019)。测量FT以及与健康相关的生活质量（HRQoL）代表了一种临床相关且以患者为中心的方法（deSouza等人。,2017)。
目的：评估FT及其与生活质量（QoL）的关系。
方法：这是一项观察性描述性研究，在建议接受P&P治疗的癌症患者中进行。从2022年9月至2023年2月，使用官方工具对分数进行了估算：慢性疾病治疗的功能评估财务毒性评分（FACIT-COST）和欧洲癌症研究与治疗组织（EORTC）癌症生活质量问卷（QLQ30）。
结果：来自150名患者（70名男性和80名女性，平均年龄54.96±13.5岁)，92.6%遭受FT。11例患者（7.3％）低于FT等级0，41例（27.3％）为FT等级1，98例（65.3％）为FT等级2，无患者低于FT等级3。在标准α0.05(95CI)下，FT和HRQoL的全球评分显示出相关性。在住院部(IPD)费用中，药费支出最大，为33%，在门诊部(OPD)费用中，治疗费用占总费用的50%。乳腺癌（30例，20％）和口腔癌（26例，17.3％）是最常见的癌症。
结论：使用COST工具测量的FT显示与HRQoL相关。
■本文涉及癌症患者的保险政策，而不考虑P&P护理治疗。
目的：评估FT及其与生活质量（QoL）的关系。
方法：这是一项观察性描述性研究，在建议接受P&P治疗的癌症患者中进行。从2022年9月至2023年2月，使用官方工具对分数进行了估算：慢性疾病治疗的功能评估财务毒性评分（FACIT-COST）和欧洲癌症研究与治疗组织（EORTC）癌症生活质量问卷（QLQ30）。
结果：来自150名患者（70名男性和80名女性，平均年龄54.96±13.5岁)，92.6%遭受FT。11例患者（7.3％）低于FT等级0，41例（27.3％）为FT等级1，98例（65.3％）为FT等级2，无患者低于FT等级3。在标准α0.05(95CI)下，FT和HRQoL的全球评分显示出相关性。在住院部(IPD)费用中，药费支出最大，为33%，在门诊部(OPD)费用中，治疗费用占总费用的50%。乳腺癌（30例，20％）和口腔癌（26例，17.3％）是最常见的癌症。
结论：使用COST工具测量的FT显示与HRQoL相关。
■本文涉及癌症患者的保险政策，而不考虑P&P护理治疗。
