PDF(Pubmed)
Abstract：
Medulloblastoma accounts for nearly 10% of childhood primary central nervous system (CNS) malignancies. However, it is rare in adults. Extracranial metastasis is commonly documented to involve bones but rarely involves lymph nodes. Herein, we present an unusual case of primary CNS medulloblastoma in an adult patient with extracranial metastasis to a lymph node, which exhibits a myogenic differentiation. To the best of our knowledge, this is the fourth reported case of medulloblastoma in an adult with extracranial metastasis to the lymph node and the first reported case of extracranial metastatic medulloblastoma with myogenic differentiation that involves a lymph node.
摘要：
髓母细胞瘤占儿童原发性中枢神经系统（CNS）恶性肿瘤的近10％。然而,这在成年人中很少见。颅外转移通常涉及骨骼，但很少涉及淋巴结。在这里，我们介绍了一例罕见的原发性中枢神经系统髓母细胞瘤的成人患者的颅外淋巴结转移，表现出肌源性分化。据我们所知,这是第4例报道的成人髓母细胞瘤颅外转移至淋巴结，也是第1例报道的颅外转移性髓母细胞瘤伴有淋巴结的肌源性分化。
