关键词: Infection Local antibiotics Orthopedic trauma Tobramycin Vancomycin

Mesh : Humans Anti-Bacterial Agents / therapeutic use Retrospective Studies Fracture Fixation, Internal / adverse effects methods Surgical Wound Infection / etiology prevention & control Hip Fractures / surgery Acetabulum / surgery Treatment Outcome

来  源:   DOI:10.1007/s00590-023-03789-3

Abstract:
Postoperative surgical site infections remain a significant and prevalent complication after open reduction and internal fixation of acetabular fractures. Local antibiotics have been shown to decrease risk of postoperative infection, although recent evidence is conflicting. We provide a consistent and replicable technique for delivering intraoperative broad-spectrum antibiotics in the form of a putty applied directly to surgical implants. With this technique, systemic levels of those antibiotics remain safe and stable.
摘要:
髋臼骨折切开复位内固定术后手术部位感染仍然是重要且普遍的并发症。局部抗生素已被证明可以降低术后感染的风险,尽管最近的证据相互矛盾。我们提供了一种一致且可复制的技术,以直接应用于外科植入物的腻子形式提供术中广谱抗生素。有了这项技术,这些抗生素的全身水平保持安全和稳定.
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