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Abstract：
Antimicrobial resistance (AMR) is considered a One Health (OH) challenge, ideally demanding concerted efforts from the animal, human and environmental side. DANMAP, the Danish Integrated Antimicrobial Resistance Monitoring and Research Program, is monitoring AMR and antimicrobial use in animals and humans. OH-EpiCap is an evaluation tool, developed to address essential elements in OH surveillance systems, such as the dimensions of the organization, operational activities and the impact of the surveillance activities. We aimed to evaluate DANMAP using OH-EpiCap and hereby assessed the suitability of OH-EpiCap to evaluate integrated AMR surveillance systems. During the evaluation, the strengths and weaknesses of DANMAP concerning the \"OH-ness\" of the program were discussed. Furthermore, possible adaptations of the standard operating procedures and governance structure were addressed. Attention was paid to the ability and easiness of DANMAP to cope with current and future challenges connected to integrated AMR surveillance. It was concluded that DANMAP has a strong OH approach covering relevant aspects for humans and animals, whereas environmental aspects are missing. OH-EpiCap proved to be straightforward to use and provided valuable insights. The authors recommend OH-EpiCap to be used by health authorities and stakeholders. It is not suitable for the technical evaluation of a surveillance program.
摘要：
抗菌素耐药性(AMR)被认为是一个单一健康(OH)挑战，理想情况下需要动物的共同努力，人类和环境方面。DANMAP,丹麦抗菌素耐药性综合监测和研究计划，正在监测动物和人类的AMR和抗菌药物的使用。OH-EpiCap是一种评估工具，旨在解决OH监视系统中的基本要素，例如组织的维度，业务活动和监督活动的影响。我们旨在使用OH-EpiCap评估DANMAP，并在此评估OH-EpiCap评估综合AMR监测系统的适用性。在评估过程中,讨论了DANMAP关于该计划的“OH-ness”的优缺点。此外，解决了标准作业程序和治理结构的可能调整。关注DANMAP应对与综合AMR监测相关的当前和未来挑战的能力和容易性。结论是，DANMAP具有强大的OH方法，涵盖了人类和动物的相关方面，而环境方面却缺失。OH-EpiCap被证明是直接使用，并提供了有价值的见解。作者建议卫生当局和利益相关者使用OH-EpiCap。它不适合对监视程序进行技术评估。
