Abstract:
The Plant Expression Omnibus (PEO) is a web application that provides biologists with access to gene expression insights across over 100 plant species, ~60 000 manually annotated RNA-seq samples, and more than 4 million genes. The tool allows users to explore the expression patterns of genes across different organs, identify organ-specific genes, and discover top co-expressed genes for any gene of interest. PEO also provides functional annotations for each gene, allowing for the identification of genetic modules and pathways. PEO is designed to facilitate comparative kingdom-wide gene expression analysis and provide a valuable resource for plant biology research. We provide two case studies to demonstrate the utility of PEO in identifying candidate genes in pollen coat biosynthesis in Arabidopsis and investigating the biosynthetic pathway components of capsaicin in Capsicum annuum. The database is freely available at https://expression.plant.tools/.
摘要:
植物表达Omnibus(PEO)是一个Web应用程序,为生物学家提供了超过100种植物物种的基因表达见解。~60000个手动注释的RNA-seq样本,和超过400万个基因。该工具允许用户探索基因在不同器官中的表达模式,识别器官特异性基因,并发现任何感兴趣的基因的最高共表达基因。PEO还为每个基因提供功能注释,允许识别遗传模块和途径。PEO旨在促进比较王国范围的基因表达分析,并为植物生物学研究提供宝贵的资源。我们提供了两个案例研究,以证明PEO在鉴定拟南芥花粉被生物合成中的候选基因以及研究辣椒中辣椒素的生物合成途径成分中的实用性。该数据库可在https://expression上免费获得。植物。工具/。