PDF(Pubmed)
Abstract：
Perianal/perineal rhabdomyosarcomas (PRMS) is rare, and the outcome is poor. A 29-year-old female presented with perineal rhabdomyosarcomas revealed metastases to inguinal lymph nodes on the bilateral side. Disease progression was discovered when the patient got adjuvant epirubicin, ifosfamide, and bevacizumab for 2 cycles. After 3 cycles of nivolumab, dacarbazine, cisplatin, and vinblastine therapy, a partial response was identified in the patient. The surgical resection was performed. The patient received neoadjuvant chemotherapy before surgery and was weak after surgery, so he did not receive chemoradiotherapy. The patient succumbed after 11 months postoperatively due to widespread intraabdominal metastasis.
摘要：
肛周/会阴横纹肌肉瘤（PRMS）很少见，结果很差。一名29岁的女性出现会阴横纹肌肉瘤，发现双侧腹股沟淋巴结转移。当患者接受辅助表柔比星治疗时，发现疾病进展，异环磷酰胺,贝伐单抗治疗2个周期。经过3个周期的nivolumab，达卡巴嗪,顺铂,和长春碱治疗,患者出现部分缓解.进行手术切除。患者术前接受新辅助化疗，术后虚弱，所以他没有接受放化疗。由于广泛的腹腔内转移，患者在术后11个月后死亡。
