PDF(Pubmed)
Abstract：
UNASSIGNED: In patients with appropriate epidemiological risk factors, neurocysticecosis should be considered as part of the differential diagnosis of suprasellar or parasellar mass lesions. As neuroimaging findings can be nonspecific, serology may be helpful, but when still in doubt, brain biopsy, and histopathology may be necessary to make the correct diagnosis.
UNASSIGNED: Neurocysticercosis (NCC) is a well-documented central nervous system helminth infection that is, frequently observed in developing countries. Known sites of NCC infection include the highly vascular gray-white matter junction, basal cistern, brain parenchyma, subarachnoid space, ventricular system, and spinal cord. This case highlights an uncommon yet intriguing site of NCC infection within the suprasellar area, which presented with similar clinical and imaging characteristics as suprasellar masses or lesions. The 44-year-old female initially complained of headaches and nausea that persisted for 5 years and progressed to vision problems and short-term memory loss. A craniopharyngioma was initially suspected, based on imaging findings of a partially calcified suprasellar tumor. However, cysticercosis was confirmed by histopathology and serological testing positive for Cysticercus IgG antibodies. The patient was successfully treated with albendazole and tapering doses of steroids, which improved her presenting symptoms and resolved prior imaging findings. This case serves as a reminder to consider NCC in the differential diagnosis of sellar and suprasellar masses or lesions, particularly when an epidemiologic risk factor is present.
UNASSIGNED: Neurocysticercosis (NCC) is a well-documented central nervous system helminth infection that is, frequently observed in developing countries. Known sites of NCC infection include the highly vascular gray-white matter junction, basal cistern, brain parenchyma, subarachnoid space, ventricular system, and spinal cord. This case highlights an uncommon yet intriguing site of NCC infection within the suprasellar area, which presented with similar clinical and imaging characteristics as suprasellar masses or lesions. The 44-year-old female initially complained of headaches and nausea that persisted for 5 years and progressed to vision problems and short-term memory loss. A craniopharyngioma was initially suspected, based on imaging findings of a partially calcified suprasellar tumor. However, cysticercosis was confirmed by histopathology and serological testing positive for Cysticercus IgG antibodies. The patient was successfully treated with albendazole and tapering doses of steroids, which improved her presenting symptoms and resolved prior imaging findings. This case serves as a reminder to consider NCC in the differential diagnosis of sellar and suprasellar masses or lesions, particularly when an epidemiologic risk factor is present.
摘要：
■在具有适当流行病学危险因素的患者中，应将神经囊虫病作为鞍上或鞍旁肿块病变的鉴别诊断的一部分。由于神经影像学检查结果可能是非特异性的，血清学可能会有所帮助，但是当仍然有疑问时，脑活检,和组织病理学可能需要做出正确的诊断。
■神经囊虫病（NCC）是一种有据可查的中枢神经系统蠕虫感染，经常在发展中国家观察到。NCC感染的已知部位包括高血管灰白质交界处，基底水箱，脑实质,蛛网膜下腔,心室系统,和脊髓。此病例突出显示了鞍上区域内NCC感染的罕见但有趣的部位，表现为与鞍上肿块或病变相似的临床和影像学特征。这位44岁的女性最初抱怨头痛和恶心，持续了5年，并发展为视力问题和短期记忆丧失。最初怀疑是颅咽管瘤，基于部分钙化的鞍上肿瘤的影像学表现。然而,通过组织病理学和血清学检测囊尾蚴IgG抗体阳性证实囊尾蚴病。患者成功接受了阿苯达唑和逐渐减少剂量的类固醇治疗，这改善了她的表现症状并解决了先前的影像学发现。此病例提醒在鞍区和鞍区上肿块或病变的鉴别诊断中考虑NCC,特别是当存在流行病学危险因素时。
■神经囊虫病（NCC）是一种有据可查的中枢神经系统蠕虫感染，经常在发展中国家观察到。NCC感染的已知部位包括高血管灰白质交界处，基底水箱，脑实质,蛛网膜下腔,心室系统,和脊髓。此病例突出显示了鞍上区域内NCC感染的罕见但有趣的部位，表现为与鞍上肿块或病变相似的临床和影像学特征。这位44岁的女性最初抱怨头痛和恶心，持续了5年，并发展为视力问题和短期记忆丧失。最初怀疑是颅咽管瘤，基于部分钙化的鞍上肿瘤的影像学表现。然而,通过组织病理学和血清学检测囊尾蚴IgG抗体阳性证实囊尾蚴病。患者成功接受了阿苯达唑和逐渐减少剂量的类固醇治疗，这改善了她的表现症状并解决了先前的影像学发现。此病例提醒在鞍区和鞍区上肿块或病变的鉴别诊断中考虑NCC,特别是当存在流行病学危险因素时。
