PDF(Pubmed)
Abstract：
UNASSIGNED: Cardiac masses encompass a wide differential including primary and secondary malignancies and can present with a variety of symptoms, many of which are non-specific. Early identification and classification are important, particularly for cardiac malignancies such as sarcomas as these are aggressive tumours with exceptionally poor prognoses when metastases are present at diagnosis.
UNASSIGNED: We report two cases of patients who presented with dyspnoea and were diagnosed with cardiac sarcomas; the former a primary sarcoma (undifferentiated pleomorphic subtype) and the latter a secondary sarcoma (round cell myxoid liposarcoma) that serve as comparisons for presentation and management of different types of this disease. Computed Tomography (CT) and echocardiography imaging findings are demonstrated showing the typical location and morphology of each subtype.
UNASSIGNED: Cardiac sarcomas are the most common primary cardiac malignancy, of which undifferentiated pleomorphic sarcoma is a common subtype. Undifferentiated pleomorphic sarcomas are aggressive, have a tendency to arise in the left atrium, and can appear similar to benign cardiac masses. Round cell myxoid liposarcomas by contrast are rare causes of secondary cardiac malignancies, metastasizing to the heart from soft tissues. Both diagnoses carry poor prognoses and although rare, are important to recognize as timely intervention with surgery, radiotherapy, and consideration of chemotherapy is key to maximizing survival.
UNASSIGNED: We report two cases of patients who presented with dyspnoea and were diagnosed with cardiac sarcomas; the former a primary sarcoma (undifferentiated pleomorphic subtype) and the latter a secondary sarcoma (round cell myxoid liposarcoma) that serve as comparisons for presentation and management of different types of this disease. Computed Tomography (CT) and echocardiography imaging findings are demonstrated showing the typical location and morphology of each subtype.
UNASSIGNED: Cardiac sarcomas are the most common primary cardiac malignancy, of which undifferentiated pleomorphic sarcoma is a common subtype. Undifferentiated pleomorphic sarcomas are aggressive, have a tendency to arise in the left atrium, and can appear similar to benign cardiac masses. Round cell myxoid liposarcomas by contrast are rare causes of secondary cardiac malignancies, metastasizing to the heart from soft tissues. Both diagnoses carry poor prognoses and although rare, are important to recognize as timely intervention with surgery, radiotherapy, and consideration of chemotherapy is key to maximizing survival.
摘要：
■心脏肿块包括广泛的差异，包括原发性和继发性恶性肿瘤，并可表现出多种症状，其中许多是非特定的。早期识别和分类很重要，特别是对于心脏恶性肿瘤，如肉瘤，因为当诊断时存在转移时，这些肿瘤是侵袭性肿瘤，预后异常差。
■我们报告了2例呼吸困难并被诊断为心脏肉瘤的患者；前者是原发性肉瘤（未分化的多形性亚型），后者是继发性肉瘤（圆形细胞黏液样脂肪肉瘤），可作为不同类型该病的表现和治疗的比较。证明了计算机断层扫描（CT）和超声心动图成像发现，显示了每种亚型的典型位置和形态。
■心脏肉瘤是最常见的原发性心脏恶性肿瘤，其中未分化多形性肉瘤是一种常见亚型。未分化多形性肉瘤具有侵袭性，有出现在左心房的趋势，并且可能看起来类似于良性心脏肿块。相反，圆形细胞黏液样脂肪肉瘤是继发性心脏恶性肿瘤的罕见原因，从软组织转移到心脏。两种诊断都有不良的预后，尽管罕见，重要的是要认识到及时干预手术，放射治疗,考虑化疗是最大限度地提高生存率的关键。
■我们报告了2例呼吸困难并被诊断为心脏肉瘤的患者；前者是原发性肉瘤（未分化的多形性亚型），后者是继发性肉瘤（圆形细胞黏液样脂肪肉瘤），可作为不同类型该病的表现和治疗的比较。证明了计算机断层扫描（CT）和超声心动图成像发现，显示了每种亚型的典型位置和形态。
■心脏肉瘤是最常见的原发性心脏恶性肿瘤，其中未分化多形性肉瘤是一种常见亚型。未分化多形性肉瘤具有侵袭性，有出现在左心房的趋势，并且可能看起来类似于良性心脏肿块。相反，圆形细胞黏液样脂肪肉瘤是继发性心脏恶性肿瘤的罕见原因，从软组织转移到心脏。两种诊断都有不良的预后，尽管罕见，重要的是要认识到及时干预手术，放射治疗,考虑化疗是最大限度地提高生存率的关键。
