PDF(Pubmed)
Abstract：
UNASSIGNED: This study aimed to determine if the presence of a pericardial effusion is associated with adverse outcomes among children admitted with juvenile idiopathic arthritis.
UNASSIGNED: The multicenter, retrospective cohort study was conducted with 4,332 patients (1,554 males, 2,778 females; median age: 12 years; IQR, 7, 15 years) using the Pediatric Health Information System. Data from hospital admissions between January 1, 2004, and September 15, 2015, were obtained for patients with an International Disease Classification, Ninth Revision code for juvenile idiopathic arthritis. Pericardial effusion was the primary predictor variable; the outcomes of interest were length of stay, hospital costs, and readmission within 90 days. Multivariate models were created to evaluate associations between pericardial effusion and adverse outcomes. We also analyzed factors associated with increased odds of having pericardial effusion in juvenile idiopathic arthritis.
UNASSIGNED: One hundred twenty (3%) patients had a code for pericardial effusion. Children with pericardial effusion had a longer median length of stay (7 days (IQR 3, 12) vs. 3 days (IQR 2,6), p<0.001), higher median costs ($17,688 (IQR 8,657, 40,623) vs. $8,456 (IQR 4,865, 16,302), p<0.001), and greater rates of readmission (22% vs. 15%, p=0.045). Multivariate analysis demonstrated no significant association between pericardial effusion and outcomes of interest. Black race and male sex were associated with increased odds of having pericardial effusion.
UNASSIGNED: Pericardial effusion is rare among children admitted with juvenile idiopathic arthritis but is associated with significant morbidity; its presence may be a marker of disease severity. Black children and males admitted with juvenile idiopathic arthritis warrant special consideration and may benefit from screening echocardiography.
UNASSIGNED: The multicenter, retrospective cohort study was conducted with 4,332 patients (1,554 males, 2,778 females; median age: 12 years; IQR, 7, 15 years) using the Pediatric Health Information System. Data from hospital admissions between January 1, 2004, and September 15, 2015, were obtained for patients with an International Disease Classification, Ninth Revision code for juvenile idiopathic arthritis. Pericardial effusion was the primary predictor variable; the outcomes of interest were length of stay, hospital costs, and readmission within 90 days. Multivariate models were created to evaluate associations between pericardial effusion and adverse outcomes. We also analyzed factors associated with increased odds of having pericardial effusion in juvenile idiopathic arthritis.
UNASSIGNED: One hundred twenty (3%) patients had a code for pericardial effusion. Children with pericardial effusion had a longer median length of stay (7 days (IQR 3, 12) vs. 3 days (IQR 2,6), p<0.001), higher median costs ($17,688 (IQR 8,657, 40,623) vs. $8,456 (IQR 4,865, 16,302), p<0.001), and greater rates of readmission (22% vs. 15%, p=0.045). Multivariate analysis demonstrated no significant association between pericardial effusion and outcomes of interest. Black race and male sex were associated with increased odds of having pericardial effusion.
UNASSIGNED: Pericardial effusion is rare among children admitted with juvenile idiopathic arthritis but is associated with significant morbidity; its presence may be a marker of disease severity. Black children and males admitted with juvenile idiopathic arthritis warrant special consideration and may benefit from screening echocardiography.
摘要：
■本研究旨在确定心包积液的存在是否与青少年特发性关节炎患儿的不良后果有关。
■多中心，回顾性队列研究对4,332例患者(1,554例男性，2778名女性；平均年龄：12岁；IQR，7、15年)使用儿科健康信息系统。2004年1月1日至2015年9月15日期间的住院数据是针对具有国际疾病分类的患者获得的。青少年特发性关节炎第九次修订代码。心包积液是主要预测变量；感兴趣的结果是住院时间，医院费用,并在90天内重新接纳。建立多变量模型以评估心包积液与不良结局之间的关联。我们还分析了幼年特发性关节炎心包积液几率增加的相关因素。
■一百二十（3％）患者有心包积液的代码。心包积液患儿中位住院时间较长（7天（IQR3，12）vs.3天（IQR2,6），p<0.001)，成本中位数较高（17,688美元（1657，40623美元）与$8,456（IQR4,865，16,302），p<0.001)，和更高的再入院率(22%与15%,p=0.045)。多变量分析显示心包积液与目标结局之间无显著关联。黑人种族和男性与心包积液的几率增加有关。
心包积液在青少年特发性关节炎患儿中很少见，但与显著的发病率相关；它的存在可能是疾病严重程度的标志。患有青少年特发性关节炎的黑人儿童和男性需要特别考虑，并且可能会从超声心动图筛查中受益。
■多中心，回顾性队列研究对4,332例患者(1,554例男性，2778名女性；平均年龄：12岁；IQR，7、15年)使用儿科健康信息系统。2004年1月1日至2015年9月15日期间的住院数据是针对具有国际疾病分类的患者获得的。青少年特发性关节炎第九次修订代码。心包积液是主要预测变量；感兴趣的结果是住院时间，医院费用,并在90天内重新接纳。建立多变量模型以评估心包积液与不良结局之间的关联。我们还分析了幼年特发性关节炎心包积液几率增加的相关因素。
■一百二十（3％）患者有心包积液的代码。心包积液患儿中位住院时间较长（7天（IQR3，12）vs.3天（IQR2,6），p<0.001)，成本中位数较高（17,688美元（1657，40623美元）与$8,456（IQR4,865，16,302），p<0.001)，和更高的再入院率(22%与15%,p=0.045)。多变量分析显示心包积液与目标结局之间无显著关联。黑人种族和男性与心包积液的几率增加有关。
心包积液在青少年特发性关节炎患儿中很少见，但与显著的发病率相关；它的存在可能是疾病严重程度的标志。患有青少年特发性关节炎的黑人儿童和男性需要特别考虑，并且可能会从超声心动图筛查中受益。
