关键词: Burn Fusariosis Invasive fungal infection Stubble burning

Mesh : Humans Fusariosis / diagnosis drug therapy Fusarium Antifungal Agents / therapeutic use Burns / complications

来  源:   DOI:10.1016/j.mycmed.2023.101450

Abstract:
BACKGROUND: Fusarium species can cause a broad spectrum of human infections, ranging from superficial and locally invasive to disseminated, depending on the immune status of the host and portal of entry. Although several cases of cutaneous fusariosis in burn victims have been reported, molecular identification for pathogen recognition has been used only in a few cases.
METHODS: In this report, we describe an uncommon case of extensive primary cutaneous fusariosis caused by Fusarium keratoplasticum in a patient who sustained injuries during stubble burning.
RESULTS: A review of cases of cutaneous fusariosis in burn victims revealed that this uncommon infection could be lethal, and treatment strategies should focus on both surgical debridement and the initiation of systemic antifungal therapy. Furthermore, because skin defects can serve as a portal of entry for Fusarium species in burn victims, early and aggressive treatment is crucial to prevent serious consequences.
摘要:
背景:镰刀菌可引起广泛的人类感染,从表面和局部侵入性到传播性,取决于宿主和入口的免疫状态。尽管已经报道了几例烧伤患者的皮肤镰刀菌病,用于病原体识别的分子鉴定仅在少数情况下使用。
方法:在本报告中,我们描述了一例罕见的由镰刀菌角化镰刀菌引起的广泛原发性皮肤镰刀菌病,该患者在残茬燃烧期间受伤。
结果:对烧伤患者皮肤镰刀菌病病例的回顾表明,这种罕见的感染可能是致命的,治疗策略应同时关注手术清创和全身抗真菌治疗.此外,因为皮肤缺陷可以作为烧伤受害者镰刀菌进入的门户,早期积极治疗对防止严重后果至关重要。
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