METHODS: This study included male patients with lower urinary tract symptoms. We categorized the patients into the nonnocturnal polyuria (non-NP) group (≤0.33) and the NP group (>0.33) based on the nocturnal polyuria index from the frequency volume chart. We measured the 24-h diurnal blood pressure and compared the two groups.
RESULTS: Among 90 patients, 46 in the non-NP group and 44 in the NP group were included. There was no significant difference in the systolic and diastolic blood pressure during waking time between the two groups; however, the degree of systolic blood pressure reduction during sleep time in the NP group was significantly less than that in the non-NP group (p = 0.039). In the multivariate analysis, systolic BP during sleep was significantly associated with NP (OR 0.970, p = 0.028).
CONCLUSIONS: NP is associated with inadequate nocturnal blood pressure reduction in males, suggesting that reduction in nocturnal blood pressure may lead to improvement in nocturia.
方法:本研究包括有下尿路症状的男性患者。我们根据频率容量图中的夜间多尿指数将患者分为非夜间多尿(非NP)组(≤0.33)和NP组(>0.33)。我们测量了24小时的昼夜血压,并比较了两组。
结果:在90例患者中,包括非NP组中的46例和NP组中的44例。苏醒时两组的收缩压和舒张压无显著差异;NP组睡眠时收缩压下降程度明显小于非NP组(p=0.039).在多变量分析中,睡眠时收缩压与NP显著相关(OR0.970,p=0.028).
结论:NP与男性夜间血压降低不足有关,提示夜间血压的降低可能导致夜尿症的改善。