OBJECTIVE: Aortic annular plane systolic excursion is lower in cats with HCM compared to control cats, and cats in stage C have the lowest AAPSE.
METHODS: One hundred seventy-five cats: 60 normal, 61 HCM stage B and 54 HCM stage C cats.
METHODS: Multicenter retrospective case-control study. Electronic medical records from 4 referral hospitals were reviewed for cats diagnosed with HCM and normal cats. HCM was defined as LV wall thickness ≥6 mm and normal cats ≤5 mm. M-mode bisecting the aorta in right parasternal short-axis view was used to measure AAPSE.
RESULTS: Aortic annular plane systolic excursion was lower in HCM cats compared to normal cats (3.9 ± 0.9 mm versus 4.6 ± 0.9 mm, P < .001) and was lowest in HCM stage C (2.4 ± 0.6 mm, P < .001). An AAPSE <2.9 mm gave a sensitivity of 83% (95% CI 71%-91%) and specificity of 92% (95% CI 82%-97%) to differentiate HCM stage C from stage B. AAPSE correlated with mitral annular plane systolic excursion (r = .6 [.4-.7], P < .001), and atrial fractional shortening (r = .6 [.5-.7], P < .001), but showed no correlation with LV fractional shortening.
CONCLUSIONS: Aortic annular plane systolic excursion is an easily acquired echocardiographic variable and might be a new measurement of LV systolic performance in cats with HCM.
目的:与对照猫相比,患有HCM的猫的主动脉环平面收缩期偏移较低,C阶段的猫的AAPSE最低。
方法:一百七十五只猫:60只正常,61只HCMB期猫和54只HCMC期猫。
方法:多中心回顾性病例对照研究。对于诊断为HCM的猫和正常猫,对4家转诊医院的电子病历进行了审查。HCM定义为LV壁厚≥6mm,正常猫≤5mm。在右胸骨旁短轴视图中,将主动脉平分的M模式用于测量AAPSE。
结果:与正常猫相比,HCM猫的主动脉瓣环平面收缩期偏移较低(3.9±0.9mm对4.6±0.9mm,P<.001),在HCM阶段C中最低(2.4±0.6mm,P<.001)。AAPSE<2.9mm对区分HCMC期和B期的敏感性为83%(95%CI71%-91%),特异性为92%(95%CI82%-97%)。AAPSE与二尖瓣环平面收缩期偏移相关(r=.6[.4-.7],P<.001),和心房缩短分数(r=.6[.5-.7],P<.001),但与LV缩短率无相关性。
结论:主动脉瓣环平面收缩偏移是一个容易获得的超声心动图变量,可能是HCM猫左心室收缩性能的新测量。