PDF(Pubmed)
Abstract：
Intrathecal baclofen (ITB) therapy is an effective method of treating spasticity in persons with spasticity due to spinal cord injury (SCI), but complications are not rare and can include spinal fluid leaks, infection, and catheter/pump malfunction.
This study presents information related to an adult male patient with traumatic SCI and a history of two prior ITB pump pocket infections that required removal due to pump infection. The patient then developed skin erosion over the third pump, and the fluid around the pump grew methicillin-sensitive Staphylococcus aureus, diphtheroids, and Candida parapsilosis. The patient was initially treated with antibiotics and anti-fungal medication without removal of the ITB pump. The ITB pump was eventually removed 27 months later, and the fourth pump was implanted 10 months later.
ITB pumps can be an effective treatment modality for spasticity in people with SCI; however, complications, including infection, can occur and require pump removal. This case illustrates a case of possible Candida colonization of the ITB pump, which was eventually removed.
This study presents information related to an adult male patient with traumatic SCI and a history of two prior ITB pump pocket infections that required removal due to pump infection. The patient then developed skin erosion over the third pump, and the fluid around the pump grew methicillin-sensitive Staphylococcus aureus, diphtheroids, and Candida parapsilosis. The patient was initially treated with antibiotics and anti-fungal medication without removal of the ITB pump. The ITB pump was eventually removed 27 months later, and the fourth pump was implanted 10 months later.
ITB pumps can be an effective treatment modality for spasticity in people with SCI; however, complications, including infection, can occur and require pump removal. This case illustrates a case of possible Candida colonization of the ITB pump, which was eventually removed.
摘要：
背景：鞘内注射巴氯芬（ITB）疗法是治疗由于脊髓损伤（SCI）引起的痉挛患者痉挛的有效方法，但并发症并不罕见，可能包括脊髓液渗漏，感染,和导管/泵故障。
方法：本研究提供了与一名患有创伤性SCI的成年男性患者相关的信息，该患者有两次先前的ITB泵袋感染史，由于泵感染而需要切除。然后病人在第三个泵上出现皮肤侵蚀，泵周围的液体生长了对甲氧西林敏感的金黄色葡萄球菌，类白喉,和近平滑念珠菌.患者最初接受抗生素和抗真菌药物治疗，但未移除ITB泵。27个月后，ITB泵最终被拆除，10个月后植入了第四个泵。
结论：ITB泵是治疗SCI患者痉挛的有效方法；然而，并发症,包括感染,可能发生，需要泵的删除。此病例说明了ITB泵可能存在念珠菌定植的病例，最终被删除。
方法：本研究提供了与一名患有创伤性SCI的成年男性患者相关的信息，该患者有两次先前的ITB泵袋感染史，由于泵感染而需要切除。然后病人在第三个泵上出现皮肤侵蚀，泵周围的液体生长了对甲氧西林敏感的金黄色葡萄球菌，类白喉,和近平滑念珠菌.患者最初接受抗生素和抗真菌药物治疗，但未移除ITB泵。27个月后，ITB泵最终被拆除，10个月后植入了第四个泵。
结论：ITB泵是治疗SCI患者痉挛的有效方法；然而，并发症,包括感染,可能发生，需要泵的删除。此病例说明了ITB泵可能存在念珠菌定植的病例，最终被删除。
