PDF(Pubmed)
Abstract：
UNASSIGNED: The objective of this study was to compare the efficacy and safety of serratus anterior plane block (SAPB) and thoracic epidural analgesia (TEA) in thoracic region surgery.
UNASSIGNED: We implemented a systematic search of PubMed, ScienceDirect, SCOPUS, and Web of Science and through gray literature for all randomized controlled trials that compared SAPB, a novel thoracic wall nerve block, and TEA in surgery. The evaluated outcomes included the Visual Analog Scale (VAS), hypotension, and postoperative nausea and vomiting (PONV). Review Manager, version 5.4.1, was implemented for the analysis of statistics.
UNASSIGNED: The pooled analysis included six trials that fulfilled the inclusion criteria. In total 384, surgery had received regional blocks (162 - SAPB and 163 - TEA). VAS did not differ significantly between SAPB and TEA, with a mean difference of 0.71, P = 0.08. PONV incidence did not differ significantly between SAPB and TEA (odds ratio = 0.25, P = 0.07). Hypotension incidence was lower in SAPB compared to TEA (odds ratio = 0.10, P = 0.0001).
UNASSIGNED: SAPB yielded comparable VAS with TEA in pain management of thoracic region surgery. The incidence of hypotension was lower in SAPB than in TEA. No difference in PONV incidence was observed. SAPB can be a viable alternative to TEA in thoracic region surgery.
UNASSIGNED: We implemented a systematic search of PubMed, ScienceDirect, SCOPUS, and Web of Science and through gray literature for all randomized controlled trials that compared SAPB, a novel thoracic wall nerve block, and TEA in surgery. The evaluated outcomes included the Visual Analog Scale (VAS), hypotension, and postoperative nausea and vomiting (PONV). Review Manager, version 5.4.1, was implemented for the analysis of statistics.
UNASSIGNED: The pooled analysis included six trials that fulfilled the inclusion criteria. In total 384, surgery had received regional blocks (162 - SAPB and 163 - TEA). VAS did not differ significantly between SAPB and TEA, with a mean difference of 0.71, P = 0.08. PONV incidence did not differ significantly between SAPB and TEA (odds ratio = 0.25, P = 0.07). Hypotension incidence was lower in SAPB compared to TEA (odds ratio = 0.10, P = 0.0001).
UNASSIGNED: SAPB yielded comparable VAS with TEA in pain management of thoracic region surgery. The incidence of hypotension was lower in SAPB than in TEA. No difference in PONV incidence was observed. SAPB can be a viable alternative to TEA in thoracic region surgery.
摘要：
■这项研究的目的是比较前锯肌平面阻滞（SAPB）和胸段硬膜外镇痛（TEA）在胸外科手术中的有效性和安全性。
■我们对PubMed进行了系统搜索，ScienceDirect,Scopus,和WebofScience，并通过灰色文献对所有比较SAPB的随机对照试验，一种新型的胸壁神经阻滞,和TEA在手术中。评估的结果包括视觉模拟量表(VAS)，低血压,术后恶心呕吐（PONV）。审核经理,5.4.1版本，用于统计分析。
■汇总分析包括六项符合纳入标准的试验。总共384例，手术接受了区域性阻滞（162-SAPB和163-TEA）。SAPB和TEA之间的VAS没有显着差异，平均差0.71,P=0.08。SAPB和TEA之间的PONV发生率没有显着差异（比值比=0.25，P=0.07）。与TEA相比，SAPB的低血压发生率较低（比值比=0.10，P=0.0001）。
■SAPB在胸外科手术的疼痛管理中产生了与TEA相当的VAS。SAPB的低血压发生率低于TEA。没有观察到PONV发生率的差异。在胸外科手术中，SAPB可以替代TEA。
■我们对PubMed进行了系统搜索，ScienceDirect,Scopus,和WebofScience，并通过灰色文献对所有比较SAPB的随机对照试验，一种新型的胸壁神经阻滞,和TEA在手术中。评估的结果包括视觉模拟量表(VAS)，低血压,术后恶心呕吐（PONV）。审核经理,5.4.1版本，用于统计分析。
■汇总分析包括六项符合纳入标准的试验。总共384例，手术接受了区域性阻滞（162-SAPB和163-TEA）。SAPB和TEA之间的VAS没有显着差异，平均差0.71,P=0.08。SAPB和TEA之间的PONV发生率没有显着差异（比值比=0.25，P=0.07）。与TEA相比，SAPB的低血压发生率较低（比值比=0.10，P=0.0001）。
■SAPB在胸外科手术的疼痛管理中产生了与TEA相当的VAS。SAPB的低血压发生率低于TEA。没有观察到PONV发生率的差异。在胸外科手术中，SAPB可以替代TEA。
