关键词: choroidal thickness diabetic macular edema diabetic retinopathy macular thickness optical coherence tomography optical coherence tomography angiography vascular density

来  源:   DOI:10.3389/fmed.2023.1290599   PDF(Pubmed)

Abstract:
UNASSIGNED: To evaluate changes in macular status and choroidal thickness (CT) following phacoemulsification in patients with mild to moderate nonproliferative diabetic retinopathy (NPDR) using optical coherence tomography.
UNASSIGNED: In this prospective study, all of the patients underwent uncomplicated phacoemulsification. Retinal superficial capillary plexus vascular density (SCP-VD), macular thickness (MT), and CT were measured pre- and postoperatively.
UNASSIGNED: Twenty-two eyes of 22 cataract patients with mild to moderate NPDR without diabetic macular edema (DME) and 22 controls were enrolled. BCVA increased in two groups at 3 months postoperatively. At 1 and 3 months postoperatively, SCP-VD in the diabetic retinopathy (DR) group significantly increased; changes in SCP-VD in parafovea were significantly greater in the DR group than in the control group. MT and CT in the DR group significantly increased at all visits postoperatively in the fovea and perifovea. Changes in parafoveal MT were significantly greater in the DR group than in the control group at all visits postoperatively. Changes in CT and MT in the fovea were significantly greater in patients with DR than in the controls 1 and 3 months postoperatively.
UNASSIGNED: Uncomplicated phacoemulsification resulted in greater increases in SCP-VD, MT and CT in patients with early DR without preoperative DME than in controls.
摘要:
使用光学相干断层扫描技术评估轻度至中度非增殖性糖尿病视网膜病变(NPDR)患者超声乳化术后黄斑状态和脉络膜厚度(CT)的变化。
在这项前瞻性研究中,所有患者均接受了无并发症的超声乳化手术.视网膜浅表毛细血管丛血管密度(SCP-VD),黄斑厚度(MT),术前和术后测量CT。
22只眼纳入轻度至中度无糖尿病性黄斑水肿(DME)的白内障患者和22例对照。两组术后3个月BCVA均升高。术后1个月和3个月,糖尿病视网膜病变(DR)组的SCP-VD显着增加;DR组的旁瓣中SCP-VD的变化明显大于对照组。DR组的MT和CT在中央凹和中央凹术后的所有随访中均显着增加。在术后所有访问中,DR组的旁凹MT变化均显着大于对照组。术后1个月和3个月,DR患者的中央凹CT和MT的变化明显大于对照组。
不复杂的超声乳化术导致SCP-VD增加,MT和CT在没有术前DME的早期DR患者中优于对照组。
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