关键词: Laser and light sources hair removal surgery

Mesh : Female Humans Hair Removal Hair Skin Hair Follicle Lasers Proto-Oncogene Proteins c-bcl-2 / metabolism

来  源:   DOI:10.1080/14764172.2023.2284640

Abstract:
This study evaluated the effects of laser application of diverse wavelengths applied simultaneously and on different skins. The sample included two participants, a woman with light skin with abdominal hair and a woman with dark skin and hair on the inner part of the lower limbs, who received a laser therapy session. After 45 days from laser application, abdominoplasty and thigh dermolipectomy surgery were performed. In the control sample, the hair follicles were in the anagen phase, showing the presence of Bcl-2 expression. In the treated areas, follicles were observed in an advanced phase (telogen), with the presence of CK-18 and negativity of Bcl-2, highlighting the phase of hair loss at that moment and the complete apoptosis of the investigated follicle. Significant difference was observed in the comparison of the anagen phase (p = .00) and it similarly occurred in the comparison of the telogen phase (p = .00). The presence of a greater amount of follicles in the anagen phase in the control area and follicles in the telogen phase in the treated area demonstrates the efficiency of the laser at different wavelengths when reaching different skin phototypes and hair thickness, being reinforced by apoptosis and cell proliferation markers. Therefore, the hair-removal process has been optimized with various laser wavelengths.
摘要:
这项研究评估了同时应用不同波长的激光应用对不同皮肤的影响。样本包括两名参与者,一个皮肤浅,腹部有毛的女人,一个皮肤和下肢内侧有深色头发的女人,接受激光治疗的人.激光照射45天后,进行了腹部成形术和大腿真皮切除术。在对照样品中,毛囊处于生长期,显示Bcl-2表达的存在。在被治疗的区域,在晚期观察到卵泡(静止期),CK-18的存在和Bcl-2的阴性,突出了当时脱发的阶段和所研究的卵泡的完全凋亡。在生长期阶段的比较中观察到显着差异(p=.00),并且在静止期阶段的比较中也相似(p=.00)。在对照区域的生长期中存在更大量的毛囊,在治疗区域的静止期存在更大量的毛囊,证明了激光在达到不同皮肤光型和毛发厚度时在不同波长下的效率。细胞凋亡和细胞增殖标记物增强。因此,脱毛过程已与各种激光波长进行了优化。
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