Abstract：
Thyroid cancer is one of the most common tumors of the endocrine system because of its rapid and steady increase in incidence and prevalence. In recent years, a growing number of studies have identified a key role for the gut, thyroid tissue and oral microbiota in the regulation of metabolism and the immune system. A growing body of evidence has conclusively demonstrated that the microbiota influences tumor formation, prevention, diagnosis, and treatment. We provide extensive information in which oral, gut, and thyroid microbiota have an effect on thyroid cancer development in this review. In addition, we thoroughly discuss the various microbiota species, their potential functions, and the underlying mechanisms for thyroid cancer. The microbiome offers a unique opportunity to improve the effectiveness of immunotherapy and radioiodine therapy thyroid cancer by maintaining the right type of microbiota, and holds great promise for improving clinical outcomes and quality of life for thyroid cancer patients.
摘要：
甲状腺癌是内分泌系统最常见的肿瘤之一,因其发病率和患病率呈快速、稳定的上升趋势。近年来,越来越多的研究已经确定了肠道的关键作用，甲状腺组织和口腔微生物群的代谢和免疫系统的调节。越来越多的证据确凿地证明微生物群影响肿瘤的形成，预防,诊断,和治疗。我们提供广泛的信息，gut,gut和甲状腺微生物群对甲状腺癌的发展有影响。此外,我们彻底讨论了各种微生物群，它们的潜在功能，以及甲状腺癌的潜在机制。微生物组提供了一个独特的机会，通过维持正确的微生物群类型来提高免疫治疗和放射性碘治疗甲状腺癌的有效性，并对改善甲状腺癌患者的临床结局和生活质量大有希望。
