Abstract:
Introduction: Considering the positive impact of laser treatment on the proliferation of certain cell types, we opted to perform a systematic review aimed at evaluating the effects of laser therapy and photobiomodulation on the proliferation and differentiation of human dental pulp stem cells (hDPSCs). Methods: We included all research studies examining the impact of laser therapy on hDPSCs, without limitations on publication dates or article languages. The major international databases, including PubMed, ISI Web of Science, and Scopus, were searched from inception to April 2022 by the relevant keywords. Results: In total, 1886 studies were identified in the initial search from the mentioned databases and other sources. Finally, 17 relevant studies were included in the present systematic review after removing duplicates and non-relevant articles. The results indicated the useful effect of low-level laser therapy (LLLT) on the hDPSCs. Conclusion: The findings of this systematic review indicate the useful role of LLLT in cell therapy, proliferation, and differentiation associated with hDPSCs.
摘要:
简介:考虑到激光治疗对某些细胞类型的增殖的积极影响,我们选择进行系统评价,旨在评估激光治疗和光生物调节对人牙髓干细胞(hDPSCs)增殖和分化的影响.方法:我们纳入了所有研究,研究激光治疗对hDPSC的影响,对出版日期或文章语言没有限制。主要的国际数据库,包括PubMed,ISIWebofScience,还有Scopus,从成立之初到2022年4月,都通过相关关键字进行了搜索。结果:总的来说,在最初的搜索中,从上述数据库和其他来源确定了1886项研究。最后,在删除重复和非相关文章后,本系统综述中纳入了17项相关研究。结果表明低水平激光治疗(LLLT)对hDPSC的有用作用。结论:本系统综述的结果表明LLLT在细胞治疗中的有用作用。扩散,和与hDPSC相关的分化。