关键词: Guillain–Barre syndrome antilymphocyte serum antithymocyte globulin kidney transplantation polyneuropathies

来  源:   DOI:10.1002/ccr3.8184   PDF(Pubmed)

Abstract:
This report describes a rare case of developing Guillain-Barre syndrome (GBS) following receiving rabbit antithymocyte globulin (ATG) after kidney transplantation to prevent acute allograft rejection in a 34-year-old man. The patient presented severe pain in the right temporomandibular joint, fever, chills, myalgia, polyarthralgia, and bone pain. Twelve hours later, he developed quadriplegia, paresthesia, and a limited range of active motions in all extremities. No antecedent viral or bacterial infection was identified. The EMG/NCV evaluation displayed acute inflammatory sensory-motor polyneuropathy. After the administration of GBS treatment, the neurologic symptoms started to improve. Over a few days, the reflexes came back completely, and the patient was able to walk. To our knowledge, this is the second case report of ATG-related GBS after kidney transplantation.
摘要:
该报告描述了一例34岁男性在肾移植后接受兔抗胸腺细胞球蛋白(ATG)以防止急性同种异体移植排斥反应后发展为格林-巴利综合征(GBS)的罕见病例。患者右侧颞下颌关节出现剧烈疼痛,发烧,发冷,肌痛,多关节痛,和骨头疼痛。十二小时后,他出现了四肢瘫痪,感觉异常,所有四肢的活动运动范围有限。未发现先前的病毒或细菌感染。EMG/NCV评估显示急性炎性感觉运动多发性神经病。GBS治疗后,神经系统症状开始好转.几天后,反应完全恢复了,病人能走路了.据我们所知,这是肾移植后2例ATG相关GBS病例报告.
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