PDF(Pubmed)
Abstract：
An 11 years old male Labrador cross presented with unilateral vestibular signs, ipsilateral facial paresis, moderate obtundation, ptyalism, and paraparesis. MRI of the brain revealed diffuse, multifocal T2/FLAIR hyperintense changes throughout various regions of the brain including the medulla, midbrain, pons, thalamus and right cerebral hemisphere with mild multifocal contrast enhancement. The patient progressed to trismus with generalized increased extensor tone and risus sardonicus. A diagnosis of generalized tetanus was made and the patient was started on antibiotics, skeletal muscle relaxants and tetanus antitoxin and made a full recovery. To the best of the authors\' knowledge, this is the first reported case of canine tetanus in which the presenting signs involved cranial nerve dysfunction as well as the first report describing MRI changes in canine tetanus within the central nervous system.
摘要：
一名11岁的男性拉布拉多十字架出现单侧前庭体征，同侧面部麻痹,中度迟钝，ptyalism,和轻瘫.脑部MRI显示弥漫性,多灶性T2/FLAIR在包括髓质在内的大脑各个区域发生高强度变化，中脑,pons,丘脑及右侧大脑半球轻度多焦对比增强。患者进展为三联肌，并伴有广泛性伸肌张力增加和三联肌。诊断为全身性破伤风，并开始使用抗生素，骨骼肌松弛剂和破伤风抗毒素并完全康复。据作者所知，这是首例犬破伤风病例，其中出现的体征涉及颅神经功能障碍，以及首例描述犬破伤风在中枢神经系统内的MRI变化的报告。
