PDF(Pubmed)
Abstract：
Intramuscular fat (IMF) refers to the fat that accumulates between muscle bundles or within muscle cells, whose content significantly impacts the taste, tenderness, and flavor of meat products, making it a crucial economic characteristic in livestock production. However, the intricate mechanisms governing IMF deposition, involving non-coding RNAs (ncRNAs), genes, and complex regulatory networks, remain largely enigmatic. Identifying adipose tissue-specific genes and ncRNAs is paramount to unravel these molecular mysteries. This study, conducted on Jiaxian red cattle, harnessed whole transcriptome sequencing to unearth the nuances of circRNAs and miRNAs across seven distinct tissues. The interplay of these ncRNAs was assessed through differential expression analysis and network analysis. These findings are not only pivotal in unveiling the intricacies of fat deposition mechanisms but also lay a robust foundation for future research, setting the stage for enhancing IMF content in Jiaxian red cattle breeding.
摘要：
肌内脂肪（IMF）是指在肌肉束之间或肌肉细胞内积累的脂肪，其含量会显著影响味道，压痛,和肉制品的味道，使其成为畜牧业生产的重要经济特征。然而,管理国际货币基金组织存款的复杂机制，涉及非编码RNA（ncRNAs），基因，和复杂的监管网络，在很大程度上仍然是神秘的。识别脂肪组织特异性基因和ncRNAs对于解开这些分子谜团至关重要。这项研究,在嘉县红牛上进行，利用整个转录组测序来发掘circRNAs和miRNAs在七个不同组织中的细微差别。通过差异表达分析和网络分析评估这些ncRNA的相互作用。这些发现不仅对揭示复杂的脂肪沉积机制至关重要，而且为未来的研究奠定了坚实的基础。为提高嘉县红牛育种中的IMF含量奠定了基础。
