PDF(Pubmed)
Abstract：
A comorbidity of anorexia nervosa (AN) and myalgic encephalomyelitis (ME/CSF) is uncommon. A 17 years-old male adolescent with possible onset of ME/CFS after an Epstein Barr Virus infection (EBV) and later onset of AN during a second period of weight loss was twice treated off-label with metreleptin for 15 and 11 days, respectively. As in previous cases, eating disorder specific cognitions and mood improved. Interestingly, fatigue and post-exertional muscle pain (P-EMP) improved, too. We discuss potential mechanisms. Treatment with metreleptin may prove beneficial in AN and in ME/CSF associated with substantial weight loss.
摘要：
神经性厌食症（AN）和肌痛性脑脊髓炎（ME/CSF）的合并症并不常见。一名17岁的男性青少年在爱泼斯坦巴尔病毒感染（EBV）后可能出现ME/CFS，而在第二次体重减轻期间出现AN，在标签外使用metreleptin治疗了两次15天和11天，分别。与以前的情况一样，饮食失调的特定认知和情绪改善。有趣的是,疲劳和劳累后肌肉疼痛（P-EMP）得到改善，也是。我们讨论了潜在的机制。用metreleptin治疗可能证明对AN和与体重大幅减轻相关的ME/CSF有益。
