关键词: Benign bone tumor demographics epidemiology lesion orthopedic oncology

来  源:   DOI:10.4103/jfmpc.jfmpc_5_23   PDF(Pubmed)

Abstract:
UNASSIGNED: The management of benign bone lesions is controversial as it is dependent on a multitude of factors such as age, anatomic location, comorbidities, lesion metabolic activity, surgeon preferences, and goals of care, among others. Thus far, many studies have attempted to report on these lesions; however, most are heterogeneous compilations of benign and malignant lesions with nearly all failing to report patient treatment and none of which have originated from a suburban area of the United States. The goal of this study was to establish a modern database dedicated solely to benign bone tumors to reflect current diagnosis and treatment trends in suburban New York.
UNASSIGNED: This was a multicenter retrospective observational study with inclusion criteria limited to benign bone lesions of all ages. Malignant lesions were excluded. Patients were drawn from both primary care provider and surgeon records, with documentation of their associated management.
UNASSIGNED: A total of 689 patients met inclusion criteria. The overall operative rate for this cohort was 71.6%. In agreement with current literature, aneurysmal bone cysts, giant cell tumors, and osteochondromas underwent surgery more frequently than enchondromas; older patients underwent surgery less frequently; benign bone lesions were more commonly found in younger males, and the distal femur and proximal tibia were the most common locations for lesions (P < .05 for all findings).
UNASSIGNED: This study demonstrates the management of a globally representative variety of benign bone lesions in a diverse suburban population of New York and should facilitate future research on how lesion type, location, management, and other factors relate to patient outcomes.
摘要:
良性骨病变的治疗是有争议的,因为它取决于许多因素,如年龄,解剖位置,合并症,病变代谢活动,外科医生的喜好,和护理目标,在其他人中。到目前为止,许多研究试图报道这些病变;然而,大多数是良性和恶性病变的异质性汇编,几乎所有病例都没有报告患者的治疗,而且没有一个起源于美国郊区。这项研究的目的是建立一个专门针对良性骨肿瘤的现代数据库,以反映纽约郊区当前的诊断和治疗趋势。
这是一项多中心回顾性观察研究,纳入标准仅限于所有年龄段的良性骨病变。排除恶性病变。患者来自初级保健提供者和外科医生的记录,与相关管理的文档。
共有689名患者符合纳入标准。该队列的总手术率为71.6%。与目前的文献一致,动脉瘤骨囊肿,巨细胞瘤,骨软骨瘤接受手术的频率高于内生软骨瘤;老年患者接受手术的频率较低;良性骨病变更常见于年轻男性,股骨远端和胫骨近端是最常见的病变位置(所有发现P<0.05)。
这项研究展示了在纽约不同郊区人群中对具有全球代表性的各种良性骨病变的管理,并应促进对病变类型的未来研究,location,管理,和其他因素与患者预后有关。
公众号