Abstract:
Tumors of the ovarian epithelial type of testis are an infrequent entity. We report a case of borderline serous tumor in an 18-year-old male who presented with a right testicular mass, clinically suspicious of carcinoma. After right inguinal exploration, two pedunculated para-testicular masses were identified in the appendix of the right testis and epididymis. The histological features were as complex papillary structures lined by columnar cells with mild to moderate pleomorphism. Microscopically, features of borderline serous testicular tumors are identical to the morphology of the same tumors encountered in the ovarian counterparts. These tumors usually reveal papillae with fibrovascular cores lined by stratified cuboidal to columnar epithelium. This case highlights a need for clinicians and pathologists to be aware of this infrequent entity and improve the best patient management attitude. Serous epithelial tumors are common ovary tumors but are very rare entities in the testis. These tumors originate from the remnant of Mullerian ducts or Mullerian metaplasia of tunica vaginalis and are nonaggressive, even associated with extra ovarian spread, and have outstanding prognosis. A review of the literature has shown nearly fifty reported cases worldwide, and most of the cases occur in young to middle-aged adults.
摘要:
卵巢上皮型睾丸肿瘤是罕见的实体。我们报告了一例18岁男性的交界性浆液性肿瘤,表现为右睾丸肿块,临床上可疑的癌症。在右腹股沟探查后,在右睾丸和附睾的阑尾中发现了两个带束的睾丸旁肿块。组织学特征为柱状细胞内衬的复杂乳头状结构,具有轻度至中度的多态性。微观上,交界性浆液性睾丸肿瘤的特征与卵巢对应的相同肿瘤的形态相同。这些肿瘤通常显示乳头,其纤维血管核心由分层的立方体至柱状上皮衬里。这种情况凸显了临床医生和病理学家需要意识到这种罕见的实体并改善最佳的患者管理态度。浆液性上皮肿瘤是常见的卵巢肿瘤,但在睾丸中非常罕见。这些肿瘤起源于苗勒管的残余或鞘膜苗勒管化生,并且是非侵袭性的,甚至与额外的卵巢扩散有关,并有出色的预后。文献回顾显示,全世界报告了近50例病例,大多数病例发生在年轻人到中年人身上。