PDF(Pubmed)
Abstract：
Angioedema is a rare but known side effect of angiotensin-converting enzyme (ACE) inhibitor therapy. The most common presentations of ACE inhibitor-induced angioedema describe swellings in the oropharyngeal and periorbital regions. We describe a rare case of a 58-year-old female with a history of type 2 diabetes and hypertension taking lisinopril for the past three years and presented with recurrent episodes of abdominal pain, nausea, and vomiting around the same time she started taking the drug. Multiple computed tomography (CT) scans were performed, which showed findings consistent with edema in the proximal small bowel. Due to the recurrent nature of these episodes over the last three years, along with consistent findings of small bowel edema on imaging, lisinopril-induced angioedema was suspected. As a result, the patient was switched from lisinopril to amlodipine. During our follow-up with the patient, she reported that her symptoms had resolved following the withdrawal of lisinopril.
摘要：
血管性水肿是血管紧张素转换酶（ACE）抑制剂治疗的一种罕见但已知的副作用。ACE抑制剂诱导的血管性水肿的最常见表现描述口咽和眶周区域的肿胀。我们描述了一个罕见的病例，一名58岁的女性，有2型糖尿病和高血压病史，过去三年服用赖诺普利，并出现反复发作的腹痛，恶心,在她开始服药的同时呕吐。进行了多次计算机断层扫描（CT）扫描，结果显示与近端小肠水肿一致。由于这些事件在过去三年中的反复性，随着一致的小肠水肿的影像学发现，怀疑赖诺普利诱导的血管性水肿。因此,患者从赖诺普利转为氨氯地平.在我们对病人的随访中,她报告说，在赖诺普利停药后，她的症状已经缓解。
