PDF(Pubmed)
Abstract：
Lung cancer is the second most common cancer worldwide and remains the first cause of cancer death. The diagnosis of lung cancer is mostly made following evaluation for respiratory signs and symptoms but sometimes the first presentation may be atypical. Some symptoms may be related to the invasion of adjacent structures and others caused by an autoimmune-mediated process when cross-reactivity between tumor antigens and normal nervous tissues is responsible for paraneoplastic syndromes. We present a case of a young woman with a smoking history who first manifested with two uncommon presentations of lung cancer: a paraneoplastic neurological syndrome and a hemorrhagic pericardial effusion with cardiac tamponade.
摘要：
肺癌是全球第二常见的癌症，仍然是癌症死亡的第一原因。肺癌的诊断主要是在评估呼吸体征和症状后进行的，但有时首次出现可能是非典型的。当肿瘤抗原与正常神经组织之间的交叉反应导致副肿瘤综合征时，某些症状可能与相邻结构的侵入有关，而其他症状则是由自身免疫介导的过程引起的。我们介绍了一例有吸烟史的年轻女性，她首先表现为两种罕见的肺癌表现：副肿瘤神经综合征和出血性心包积液伴心脏压塞。
