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Abstract：
Tooth agenesis, one of the most common developmental defects in humans, not only impairs oral function but can also lead to craniofacial deformities. Bibliometric analysis can reveal significant shifts in research and publishing trends within specific fields. This study aims to provide a comprehensive overview of the research hotspots in tooth agenesis and predict future trends through bibliometric analysis. We searched for English-language publications related to tooth agenesis from 2001 to 2021 on the Web of Science. The publications were limited to original and review articles, and bibliometric parameters such as publication year, country, institution, author, journal, citations, and keywords were extracted and analyzed using VOSviewer, Microsoft Excel 2010, and CiteSpace. A total of 2,287 papers were ultimately selected. The results show that the USA holds a leading position in the field of tooth agenesis research. A total of 9,803 authors participated in these studies, with Alexandre R Vieira from the USA being the most prolific and most cited author. This study indicates that multidisciplinary management has become the consensus first choice for treating dental agenesis. Gene mutations related to tooth agenesis continue to be a research hotspot attracting scholarly attention. Exploring the relationship between tooth agenesis and cancer may be a future research direction. These findings contribute to potential collaborations among experts in future research on the genetic causes of tooth agenesis and tumor development and to assist the scientific community by identifying research gaps in this field.
摘要：
牙齿发育不全,人类最常见的发育缺陷之一，不仅损害口腔功能，还可能导致颅面畸形。文献计量分析可以揭示特定领域研究和出版趋势的重大变化。本研究旨在通过文献计量分析，全面概述牙齿发育不全的研究热点，并预测未来趋势。我们在科学Web上搜索了2001年至2021年与牙齿发育不全有关的英语出版物。出版物仅限于原创和评论文章，和文献计量参数，如出版年份，国家,机构,作者,journal,引文,使用VOSviewer对关键词进行了提取和分析，MicrosoftExcel2010和CiteSpace。最终共选出2,287篇论文。结果表明，美国在牙齿发育不全研究领域处于领先地位。共有9803名作者参与了这些研究，来自美国的AlexandreRVieira是最多产和被引用最多的作者。这项研究表明，多学科管理已成为治疗牙齿发育不全的共识首选。与牙齿发育不全相关的基因突变一直是学术界关注的研究热点。探索牙齿发育不全与癌症之间的关系可能是未来的研究方向。这些发现有助于专家在未来研究牙齿发育不全和肿瘤发展的遗传原因方面的潜在合作，并通过确定该领域的研究差距来帮助科学界。
