关键词: massive localized lymphedema mll morbid obesity pathophysiology secondary lymphedema surgical resection

来  源:   DOI:10.7759/cureus.47092   PDF(Pubmed)

Abstract:
Massive localized lymphedema (MLL) is an emerging clinical phenomenon predominantly observed in morbidly obese individuals. It presents both diagnostic and therapeutic challenges to clinicians due to its characterization by large, pendulous masses in the abdomen or thigh. MLL may resemble malignant conditions, such as liposarcoma, leading to unnecessary invasive interventions. This study presents two case studies: a 74-year-old male who succumbed to postoperative complications and a 56-year-old female who experienced successful recovery. These cases highlight the urgent need for robust diagnostic criteria and evidence-based management approaches for MLL. In addition, further research exploring the pathogenesis, risk factors, and potential connections among MLL, hypothyroidism, and angiosarcoma is essential.
摘要:
大规模局部淋巴水肿(MLL)是一种新兴的临床现象,主要在病态肥胖个体中观察到。它提出了诊断和治疗的挑战,临床医生由于其特点,腹部或大腿下垂的肿块。MLL可能类似于恶性疾病,比如脂肪肉瘤,导致不必要的侵入性干预。这项研究提供了两个案例研究:一名74岁的男性死于术后并发症,一名56岁的女性成功康复。这些病例凸显了对MLL的强有力的诊断标准和循证管理方法的迫切需要。此外,进一步研究探索发病机制,危险因素,以及MLL之间的潜在联系,甲状腺功能减退,血管肉瘤是必不可少的。
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