PDF(Pubmed)
Abstract：
UNASSIGNED: The International Knee Documentation Committee Subjective Knee Form (IKDC-SKF) is a knee-specific patient-reported outcome (PRO) measure that is commonly used to evaluate patients with various knee disorders. The Thai version of the IKDC-SKF (Thai IKDC-SKF) was shown to have good validity and reliability; nonetheless, no data regarding its responsiveness are available.
UNASSIGNED: To evaluate the responsiveness of the Thai IKDC-SKF for assessing patients with anterior cruciate ligament (ACL) injury and determine the minimal clinically important difference (MCID) for this PRO measure.
UNASSIGNED: Cohort study (diagnosis); Level of evidence, 3.
UNASSIGNED: This prospective study included ACL-injured patients who were scheduled for ACL reconstruction (ACLR) at a single institution. The patients completed the Thai IKDC-SKF at the baseline and the 6-month postoperative follow-up. The global rating of change scale was an anchor question that evaluated patients\' overall perception of a clinical change compared with their preoperative condition. The effect size and standardized response mean were calculated. The MCID was identified with an anchor-based approach by plotting a receiver operating characteristic curve and calculating the value that maximized the Youden index.
UNASSIGNED: Of 59 enrolled patients, 53 patients (89.8%) completed the preoperative and 6-month postoperative Thai IKDC-SKF. The mean (±SD) age of the participants was 32.3 ± 10.3 years, and 86.8% were men. The mean Thai IKDC-SKF score improved significantly from preoperatively to the 6-month follow-up (from 56.3 ± 14.9 to 70.8 ± 14.1, respectively; P < .001), with an effect size of 0.975 and a standardized response mean of 0.977. A receiver operating characteristic curve was generated to determine the ability of the Thai IKDC-SKF to distinguish between improved patients and unimproved patients, and the area under the curve was 0.80 (95% CI, 0.68-0.92), which was considered excellent. The MCID was 15.5, which yielded a sensitivity and specificity of 0.55 and 1, respectively.
UNASSIGNED: This study confirmed the responsiveness of the Thai IKDC-SKF for detecting a clinical change in ACL-injured patients after ACLR. The identified MCID of 15.5 can be used to calculate the significant clinical change and sample size in future studies.
UNASSIGNED: To evaluate the responsiveness of the Thai IKDC-SKF for assessing patients with anterior cruciate ligament (ACL) injury and determine the minimal clinically important difference (MCID) for this PRO measure.
UNASSIGNED: Cohort study (diagnosis); Level of evidence, 3.
UNASSIGNED: This prospective study included ACL-injured patients who were scheduled for ACL reconstruction (ACLR) at a single institution. The patients completed the Thai IKDC-SKF at the baseline and the 6-month postoperative follow-up. The global rating of change scale was an anchor question that evaluated patients\' overall perception of a clinical change compared with their preoperative condition. The effect size and standardized response mean were calculated. The MCID was identified with an anchor-based approach by plotting a receiver operating characteristic curve and calculating the value that maximized the Youden index.
UNASSIGNED: Of 59 enrolled patients, 53 patients (89.8%) completed the preoperative and 6-month postoperative Thai IKDC-SKF. The mean (±SD) age of the participants was 32.3 ± 10.3 years, and 86.8% were men. The mean Thai IKDC-SKF score improved significantly from preoperatively to the 6-month follow-up (from 56.3 ± 14.9 to 70.8 ± 14.1, respectively; P < .001), with an effect size of 0.975 and a standardized response mean of 0.977. A receiver operating characteristic curve was generated to determine the ability of the Thai IKDC-SKF to distinguish between improved patients and unimproved patients, and the area under the curve was 0.80 (95% CI, 0.68-0.92), which was considered excellent. The MCID was 15.5, which yielded a sensitivity and specificity of 0.55 and 1, respectively.
UNASSIGNED: This study confirmed the responsiveness of the Thai IKDC-SKF for detecting a clinical change in ACL-injured patients after ACLR. The identified MCID of 15.5 can be used to calculate the significant clinical change and sample size in future studies.
摘要：
■国际膝关节文献委员会主观膝关节表（IKDC-SKF）是一种膝关节特异性患者报告结果（PRO）测量，通常用于评估患有各种膝关节疾病的患者。泰国版本的IKDC-SKF（泰国IKDC-SKF）被证明具有良好的有效性和可靠性；尽管如此，没有关于其反应性的数据.
■评估泰国IKDC-SKF评估前交叉韧带（ACL）损伤患者的反应性，并确定该PRO测量的最小临床重要差异（MCID）。
■队列研究（诊断）；证据水平，3.
■这项前瞻性研究包括ACL损伤患者，这些患者计划在单一机构进行ACL重建（ACLR）。患者在基线和术后6个月随访时完成了泰国IKDC-SKF。变化量表的整体评级是评估患者与术前状况相比对临床变化的总体看法的一个锚定问题。计算效应大小和标准化反应平均值。通过绘制接收器工作特性曲线并计算使Youden指数最大化的值，使用基于锚的方法识别了MCID。
■在59名登记的患者中，53例患者（89.8%）完成术前和术后6个月泰国IKDC-SKF。参与者的平均（±SD）年龄为32.3±10.3岁，男性占86.8%。从术前到6个月随访，泰国IKDC-SKF平均评分显着提高（分别从56.3±14.9提高到70.8±14.1；P<.001），效应大小为0.975，标准化反应平均值为0.977。生成受试者工作特征曲线，以确定泰国IKDC-SKF区分改善患者和未改善患者的能力。曲线下面积为0.80（95%CI，0.68-0.92），这被认为是优秀的。MCID为15.5,其产生的灵敏度和特异性分别为0.55和1。
■这项研究证实了泰国IKDC-SKF对ACLR后ACL损伤患者的临床变化的检测反应。15.5的鉴定MCID可用于计算未来研究中的显著临床变化和样本量。
■评估泰国IKDC-SKF评估前交叉韧带（ACL）损伤患者的反应性，并确定该PRO测量的最小临床重要差异（MCID）。
■队列研究（诊断）；证据水平，3.
■这项前瞻性研究包括ACL损伤患者，这些患者计划在单一机构进行ACL重建（ACLR）。患者在基线和术后6个月随访时完成了泰国IKDC-SKF。变化量表的整体评级是评估患者与术前状况相比对临床变化的总体看法的一个锚定问题。计算效应大小和标准化反应平均值。通过绘制接收器工作特性曲线并计算使Youden指数最大化的值，使用基于锚的方法识别了MCID。
■在59名登记的患者中，53例患者（89.8%）完成术前和术后6个月泰国IKDC-SKF。参与者的平均（±SD）年龄为32.3±10.3岁，男性占86.8%。从术前到6个月随访，泰国IKDC-SKF平均评分显着提高（分别从56.3±14.9提高到70.8±14.1；P<.001），效应大小为0.975，标准化反应平均值为0.977。生成受试者工作特征曲线，以确定泰国IKDC-SKF区分改善患者和未改善患者的能力。曲线下面积为0.80（95%CI，0.68-0.92），这被认为是优秀的。MCID为15.5,其产生的灵敏度和特异性分别为0.55和1。
■这项研究证实了泰国IKDC-SKF对ACLR后ACL损伤患者的临床变化的检测反应。15.5的鉴定MCID可用于计算未来研究中的显著临床变化和样本量。
