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Abstract：
UNASSIGNED: Accurate assessment of carotid stenosis severity is important for proper patient management. The present study aimed to compare the evaluation of carotid stenosis severity using four duplex sonography (DUS) measurements, including peak systolic velocity (PSV), PSV ratio in stenosis and distal to stenosis (PSVICA/ICA ratio), end-diastolic velocity (EDV), and B-mode, with computed tomography angiography (CTA), and to evaluate the impact of plaque morphology on correlation between DUS and CTA.
UNASSIGNED: Consecutive patients with carotid stenosis of ≥40% examined using DUS and CTA were included. Plaque morphology was also determined using magnetic resonance imaging. Spearman\'s correlation and Kendall\'s rank correlation were used to evaluate the results.
UNASSIGNED: A total of 143 cases of internal carotid artery stenosis of ≥40% based on DUS were analyzed. The PSVICA/ICA ratio showed the highest correlation [Spearman\'s correlation r = 0.576) with CTA, followed by PSV (r = 0.526), B-mode measurement (r = 0.482), and EDV (r = 0.441; p < 0.001 in all cases]. The worst correlation was found for PSV when the plaque was calcified (r = 0.238), whereas EDV showed a higher correlation (r = 0.523). Correlations of B-mode measurement were superior for plaques with smooth surface (r = 0.677), while the PSVICA/ICA ratio showed the highest correlation in stenoses with irregular (r = 0.373) or ulcerated (r = 0.382) surfaces, as well as lipid (r = 0.406), fibrous (r = 0.461), and mixed (r = 0.403; p < 0.01 in all cases) plaques. Nevertheless, differences between the mentioned correlations were not statistically significant (p > 0.05 in all cases).
UNASSIGNED: PSV, PSVICA/ICA ratio, EDV, and B-mode measurements showed comparable correlations with CTA in evaluation of carotid artery stenosis based on their correlation with CTA results. Heavy calcifications and plaque surface irregularity or ulceration negatively influenced the measurement accuracy.
UNASSIGNED: Consecutive patients with carotid stenosis of ≥40% examined using DUS and CTA were included. Plaque morphology was also determined using magnetic resonance imaging. Spearman\'s correlation and Kendall\'s rank correlation were used to evaluate the results.
UNASSIGNED: A total of 143 cases of internal carotid artery stenosis of ≥40% based on DUS were analyzed. The PSVICA/ICA ratio showed the highest correlation [Spearman\'s correlation r = 0.576) with CTA, followed by PSV (r = 0.526), B-mode measurement (r = 0.482), and EDV (r = 0.441; p < 0.001 in all cases]. The worst correlation was found for PSV when the plaque was calcified (r = 0.238), whereas EDV showed a higher correlation (r = 0.523). Correlations of B-mode measurement were superior for plaques with smooth surface (r = 0.677), while the PSVICA/ICA ratio showed the highest correlation in stenoses with irregular (r = 0.373) or ulcerated (r = 0.382) surfaces, as well as lipid (r = 0.406), fibrous (r = 0.461), and mixed (r = 0.403; p < 0.01 in all cases) plaques. Nevertheless, differences between the mentioned correlations were not statistically significant (p > 0.05 in all cases).
UNASSIGNED: PSV, PSVICA/ICA ratio, EDV, and B-mode measurements showed comparable correlations with CTA in evaluation of carotid artery stenosis based on their correlation with CTA results. Heavy calcifications and plaque surface irregularity or ulceration negatively influenced the measurement accuracy.
摘要：
■准确评估颈动脉狭窄的严重程度对于正确的患者管理很重要。本研究旨在比较使用四种双工超声（DUS）测量对颈动脉狭窄严重程度的评估，包括峰值收缩期速度（PSV），狭窄和远端狭窄的PSV比率（PSVICA/ICA比率），舒张末期血流速度(EDV),和B模式，计算机断层扫描血管造影（CTA），评价斑块形态对DUS与CTA相关性的影响。
■连续使用DUS和CTA检查颈动脉狭窄≥40%的患者。还使用磁共振成像确定斑块形态。采用Spearman相关和Kendall等级相关对结果进行评价。
■对143例基于DUS的颈内动脉狭窄≥40%的患者进行分析。PSVICA/ICA比值与CTA的相关性最高[Spearman相关性r=0.576)，其次是PSV（r=0.526），B模式测量（r=0.482），和EDV（r=0.441；在所有情况下p<0.001）。当斑块钙化时，PSV的相关性最差(r=0.238)，而EDV表现出更高的相关性(r=0.523)。B模式测量的相关性优于表面光滑的斑块（r=0.677），而PSVICA/ICA比率在不规则（r=0.373）或溃疡（r=0.382）表面的狭窄中显示出最高的相关性，以及脂质（r=0.406），纤维状(r=0.461)，和混合(r=0.403;在所有情况下p<0.01)斑块。然而，上述相关性之间的差异无统计学意义(p>0.05).
■PSV，PSVICA/ICA比值,EDV,和B模式测量显示,根据与CTA结果的相关性,在评估颈动脉狭窄方面与CTA具有相当的相关性.严重的钙化和斑块表面不规则或溃疡会对测量准确性产生负面影响。
■连续使用DUS和CTA检查颈动脉狭窄≥40%的患者。还使用磁共振成像确定斑块形态。采用Spearman相关和Kendall等级相关对结果进行评价。
■对143例基于DUS的颈内动脉狭窄≥40%的患者进行分析。PSVICA/ICA比值与CTA的相关性最高[Spearman相关性r=0.576)，其次是PSV（r=0.526），B模式测量（r=0.482），和EDV（r=0.441；在所有情况下p<0.001）。当斑块钙化时，PSV的相关性最差(r=0.238)，而EDV表现出更高的相关性(r=0.523)。B模式测量的相关性优于表面光滑的斑块（r=0.677），而PSVICA/ICA比率在不规则（r=0.373）或溃疡（r=0.382）表面的狭窄中显示出最高的相关性，以及脂质（r=0.406），纤维状(r=0.461)，和混合(r=0.403;在所有情况下p<0.01)斑块。然而，上述相关性之间的差异无统计学意义(p>0.05).
■PSV，PSVICA/ICA比值,EDV,和B模式测量显示,根据与CTA结果的相关性,在评估颈动脉狭窄方面与CTA具有相当的相关性.严重的钙化和斑块表面不规则或溃疡会对测量准确性产生负面影响。
