PDF(Pubmed)
Abstract：
UNASSIGNED: This study compared the effect of various grafting materials on the area and volume of minerals attached to dental implants.
UNASSIGNED: In this animal study, 13 dogs were divided into three groups according to the time of sacrificing (2 months, 4 months, or 6 months). The implants were placed in oversized osteotomies, and the residual defects were filled with autograft, bovine bone graft (Cerabone), or a synthetic substitute (Osteon II). At the designated intervals, the dogs were sacrificed and the segmented implants underwent micro-computed tomography analysis. The bone-implant area (BIA) and bone-implant volume (BIV) of bone and graft material were calculated in the region of interest around the implant. The data were analyzed by two-way analysis of variance (ANOVA) at P < 0.05.
UNASSIGNED: There was no significant difference in BIA and BIV between the healing intervals for any of the grafting materials (P > 0.05). ANOVA exhibited comparable BIA and BIV between the grafting materials at 2 and 4 months after surgery (P > 0.05), although a significant difference was observed after 6 months (P < 0.05). Pairwise comparisons revealed that BIA was significantly greater in the autograft-stabilized than the synthetic-grafted sites (P = 0.035). The samples augmented with autograft also showed significantly higher BIV than those treated by the xenogenic (P = 0.017) or synthetic (P = 0.002) particles.
UNASSIGNED: All graft materials showed comparable performance in providing mineral support for implants up to 4 months after surgery. At the long-term (6-month) interval, autogenous bone demonstrated significant superiority over xenogenic and synthetic substitutes concerning the bone area and volume around the implant.
UNASSIGNED: In this animal study, 13 dogs were divided into three groups according to the time of sacrificing (2 months, 4 months, or 6 months). The implants were placed in oversized osteotomies, and the residual defects were filled with autograft, bovine bone graft (Cerabone), or a synthetic substitute (Osteon II). At the designated intervals, the dogs were sacrificed and the segmented implants underwent micro-computed tomography analysis. The bone-implant area (BIA) and bone-implant volume (BIV) of bone and graft material were calculated in the region of interest around the implant. The data were analyzed by two-way analysis of variance (ANOVA) at P < 0.05.
UNASSIGNED: There was no significant difference in BIA and BIV between the healing intervals for any of the grafting materials (P > 0.05). ANOVA exhibited comparable BIA and BIV between the grafting materials at 2 and 4 months after surgery (P > 0.05), although a significant difference was observed after 6 months (P < 0.05). Pairwise comparisons revealed that BIA was significantly greater in the autograft-stabilized than the synthetic-grafted sites (P = 0.035). The samples augmented with autograft also showed significantly higher BIV than those treated by the xenogenic (P = 0.017) or synthetic (P = 0.002) particles.
UNASSIGNED: All graft materials showed comparable performance in providing mineral support for implants up to 4 months after surgery. At the long-term (6-month) interval, autogenous bone demonstrated significant superiority over xenogenic and synthetic substitutes concerning the bone area and volume around the implant.
摘要：
■这项研究比较了各种移植材料对附着在牙科植入物上的矿物质的面积和体积的影响。
■在这项动物研究中，13只犬按牺牲时间分为三组（2个月，4个月,或6个月)。植入物被放置在过大的截骨术中，用自体移植物填充剩余的缺陷，牛骨移植物（Cerabone），或合成替代品（OsteonII）。在指定的时间间隔，处死犬,并对分段植入物进行显微计算机断层扫描分析.在植入物周围的感兴趣区域中计算骨和移植材料的骨植入物面积（BIA）和骨植入物体积（BIV）。数据采用双向方差分析(ANOVA),P<0.05。
■任何移植材料的愈合间隔之间的BIA和BIV均无显着差异（P>0.05）。术后2个月和4个月移植材料间的方差分析显示BIA和BIV具有可比性(P>0.05)。尽管6个月后观察到显着差异（P<0.05）。成对比较显示，自体移植物稳定的BIA明显高于合成移植位点（P=0.035）。用自体移植物增强的样品也显示出比由异种(P=0.017)或合成(P=0.002)颗粒处理的样品显著更高的BIV。
■所有移植材料在手术后长达4个月为植入物提供矿物质支持方面均表现出可比的性能。在长期（6个月）间隔，在植入物周围的骨面积和体积方面，自体骨显示出比异种和合成替代品的显着优势。
■在这项动物研究中，13只犬按牺牲时间分为三组（2个月，4个月,或6个月)。植入物被放置在过大的截骨术中，用自体移植物填充剩余的缺陷，牛骨移植物（Cerabone），或合成替代品（OsteonII）。在指定的时间间隔，处死犬,并对分段植入物进行显微计算机断层扫描分析.在植入物周围的感兴趣区域中计算骨和移植材料的骨植入物面积（BIA）和骨植入物体积（BIV）。数据采用双向方差分析(ANOVA),P<0.05。
■任何移植材料的愈合间隔之间的BIA和BIV均无显着差异（P>0.05）。术后2个月和4个月移植材料间的方差分析显示BIA和BIV具有可比性(P>0.05)。尽管6个月后观察到显着差异（P<0.05）。成对比较显示，自体移植物稳定的BIA明显高于合成移植位点（P=0.035）。用自体移植物增强的样品也显示出比由异种(P=0.017)或合成(P=0.002)颗粒处理的样品显著更高的BIV。
■所有移植材料在手术后长达4个月为植入物提供矿物质支持方面均表现出可比的性能。在长期（6个月）间隔，在植入物周围的骨面积和体积方面，自体骨显示出比异种和合成替代品的显着优势。
