关键词: Fetal thymus volume intrauterine growth restriction screening second trimester virtual organ computer-assisted analysis

来  源:   DOI:10.4103/jmu.jmu_34_22   PDF(Pubmed)

Abstract:
UNASSIGNED: Intrauterine growth restriction (IUGR) refers to fetuses that are small for their gestational age. There is no effective test to predict this disease. The aim of our study is whether fetal three-dimensional (3D) ultrasonography (USG)-assisted thymus volume (TV) measurement predicts IUGR cases.
UNASSIGNED: Fetal 3D USG thymus measurement between 15 and 24 weeks of gestation was performed in a total of 100 women of reproductive age. Fetal TV was measured using the virtual organ computer-assisted analysis system program. All cases were followed up in terms of pregnancy complications until delivery.
UNASSIGNED: IUGR was developed in six cases in total. In cases with IUGR, mean fetal TV was found to be statistically significantly lower than in healthy cases without it. When the fetal TV was taken as 0.1645, the sensitivity was calculated as 89.5% and the specificity as 50% for predicting IUGR. The use of low fetal volume parameters is a significant and good indicator for predicting IUGR according to the binary logistic regression analysis result.
UNASSIGNED: According to the results of this study, 3D fetal TV measurement may be used in routine second-trimester sonographic anomaly screening to predict the development of fetal IUGR. In this way, fetal mortality and morbidity caused by IUGR may be reduced.
摘要:
宫内生长受限(IUGR)是指胎龄较小的胎儿。没有有效的测试来预测这种疾病。我们研究的目的是胎儿三维(3D)超声检查(USG)辅助胸腺体积(TV)测量是否可以预测IUGR病例。
在妊娠15至24周之间对总共100名育龄妇女进行了胎儿3DUSG胸腺测量。使用虚拟器官计算机辅助分析系统程序测量胎儿电视。所有病例均随访妊娠并发症直至分娩。
IUGR总共有6例。在IUGR的情况下,发现平均胎儿电视在统计学上显着低于没有它的健康病例。当胎儿TV为0.1645时,预测IUGR的敏感性为89.5%,特异性为50%。根据二元逻辑回归分析结果,使用低胎体积参数是预测IUGR的重要且良好的指标。
根据这项研究的结果,3D胎儿TV测量可用于常规的孕中期超声异常筛查,以预测胎儿IUGR的发展。这样,由IUGR引起的胎儿死亡率和发病率可能会降低。
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