Abstract：
Congenital melanocytic nevi (CMN) are rare, pigmented birthmarks that can predispose patients to melanoma of the central nervous system and skin. Data from non-CMN melanoma cohorts suggest that vitamin D levels may be connected to outcome, prompting this study of 25-hydroxyvitamin D levels in plasma samples from 40 children with CMN. While 27% were insufficient and 13% deficient, this was representative of European populations, and UK supplementation guidelines are already in place. Our data support routine vitamin D supplementation for all CMN patients during winter months, without routine serum measurement.
摘要：
先天性黑素细胞痣（CMN）是罕见的，色素性胎记，可使患者易患中枢神经系统和皮肤的黑色素瘤。来自非CMN黑色素瘤队列的数据表明，维生素D水平可能与结果有关，促使这项研究来自40名CMN儿童的血浆样本中的25-羟基维生素D水平。27%的人不足，13%的人不足，这是欧洲人口的代表，和英国补充指南已经到位。我们的数据支持冬季期间所有CMN患者的常规维生素D补充，没有常规血清测量。
